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Botanical Extract · Aqueous Hydroglycerin · 5% Loading

Cranberry Extract

Vaccinium Macrocarpon Fruit Extract · 5% aqueous hydroglycerin stock

Formulate Labs offers a fixed 5% hydroglycerin stock of Vaccinium Macrocarpon Fruit Extract, a powerful botanical active rich in A-type proanthocyanidins (PACs), anthocyanins, and low-molecular-weight biopeptides. Unlike specialized trade-named derivatives like Peptilium®, Cranberry Pro®, or Neo Actipone®, our INCI-pure extract provides comprehensive skin benefits rooted in robust scientific evidence.

  • Fixed 5% Vaccinium Macrocarpon Fruit Extract in Water + Propanediol + Glycerin Extract or Hydroglycerin Extract base
  • Four preservation systems - 8 recipes total, all made-to-order
  • COA + SDS + TDS per base/preservative variant · 500 g to 17 kg
Base: Water + Propanediol + Glycerin Extract Full composition
Preservation: Linatural MBS-4 INCI breakdown
Aqueous stock with water, propanediol, and glycerin carrying 5% botanical extract. Balanced humectancy with propanediol solubilization - default for antioxidant, anti-aging, and firming serums and toners. Preserved with Linatural MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this stock, ordered by %)
Water, Propanediol, Glycerin, Vaccinium Macrocarpon Fruit Extract, Propanediol, Ethylhexylglycerin, Benzoic Acid
Size: 500 g Formulation guide
1
Cranberry Extract
Rich in PACs, anthocyanins & biopeptides
COA & SDS
Every batch
Cosmetic grade
Aqueous hydroglycerin
Specifications

Everything you need on the technical data sheet.

INCI Name
Vaccinium Macrocarpon Fruit Extract
Common names
Cranberry Extract · Vaccinium macrocarpon fruit powder
Loading
5% extract in hydroglycerin stock
Solubility
Aqueous / water phase
Appearance
Amber to brown aqueous fluid
pH (bulk material)
4.5 – 5.1
Add at
Cool-down < 40–45 °C
Shelf Life
12–18 mo RT · 18–24 mo refrigerated
vaccinium botanical extract - vaccinium hydroglycerin stock Vaccinium Macrocarpon Fruit Extract is recognized for its rich profile of antioxidants and biopeptides, supporting skin health.
The extract

Unlocking Skin's Potential with Cranberry Extract

Vaccinium Macrocarpon Fruit Extract, derived from the cranberry (Vaccinium macrocarpon) fruit, is a versatile botanical active. While the market features numerous branded derivatives such as Peptilium®-class, Cranberry Pro®-class, and Neo Actipone®-class actives, Formulate Labs provides the pure INCI material, Vaccinium Macrocarpon Fruit Extract, in an optimized suspension, not a specific supplier SKU.

Dual mechanism: Vaccinium Macrocarpon Fruit Extract delivers high-performance cosmetic benefits through its rich concentration of A-type proanthocyanidins (PACs), anthocyanins, and low-molecular-weight biopeptides. These compounds act as potent antioxidants, scavenging reactive oxygen species (ROS) to protect the skin from environmental stressors, which helps to downregulate inflammatory cascades and neutralize metalloproteinases. Additionally, the extract's unique biopeptides support extracellular matrix (ECM) remodeling by upregulating structural genes like EDAR, stimulating collagen synthesis and reinforcing the epidermal barrier for improved skin firmness and texture.

Use levels: For Formulate Labs' fixed 5% hydroglycerin stock of Vaccinium Macrocarpon Fruit Extract, typical incorporation rates range from 5% to 10% in final cosmetic formulations for comprehensive benefits, consistent with recommendations for standard liquid extracts. For formulations seeking the more targeted effects of purified biopeptide fractions, higher concentrations of our stock may be explored, noting that these fractions are effective at 0.5–2% of pure active.

Market context: The market for Vaccinium Macrocarpon Fruit Extract includes several specialized grades, each positioned with distinct marketing claims. Examples include Peptilium®-class actives, marketed as a natural retinol alternative for anti-aging; Cranberry Pro®-class actives, focused on microbiome-friendly applications and managing cutaneous biofilms; and Neo Actipone®-class actives, which emphasize gentle AHA-like exfoliation, sebum regulation, and skin brightening from upcycled juice by-products.

Pricing context: Public B2B pricing for highly purified, cosmetic-grade peptide or protein suspensions of Vaccinium macrocarpon is sparse. While commodity-grade bulk fruit powder extracts (standardized to 25% proanthocyanidins) typically range from $10/kg to $56/kg, advanced hydroglycerin cosmetic fractions, purified for enhanced efficacy and peptide content, command a significant clinical-grade premium. Formulate Labs' 500 g sample is $165, 1 kg is $255, and a 17 kg pail is $205/kg.

We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*

5%
Fixed extract loading
2
Hydroglycerin bases
4
Preservation options
Aqueous
Water-phase compatible
Ingredient deck assessment

What this material is and isn’t.

Botanical
Leaf/stem extract; pentacyclic triterpene saponins
Aqueous stock
Hydroglycerin carrier; water phase
Cruelty-free
No animal testing in our process
Cosmetic grade
For professional formulation use

This product is sold as the INCI Vaccinium Macrocarpon Fruit Extract, distinct from market trade names (e.g., Peptilium®, Cranberry Pro®, Neo Actipone®).

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Environmental Protection
Potent antioxidants like PACs and anthocyanins actively scavenge reactive oxygen species (ROS), safeguarding skin from environmental stressors.
Collagen Synthesis & Firmness
Unique biopeptides support extracellular matrix remodeling and stimulate collagen synthesis, helping to reinforce the epidermal barrier for improved skin firmness and texture.
Skin Soothing & Comfort
Helps to downregulate inflammatory cascades and reduces UVB-induced erythema, contributing to a calmer, more comfortable skin appearance.
Supports Natural Repair
Demonstrably supports the skin's natural repair functions and accelerates renewal processes, promoting a healthy-aging appearance.

* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.

Published research

Peer-reviewed literature for due diligence.

Vaccinium Macrocarpon Fruit Extract is a highly researched botanical, with peer-reviewed studies highlighting its dense concentration of A-type proanthocyanidins, anthocyanins, and biopeptides. Research supports its role in improving skin elasticity, reducing UV-induced redness, accelerating natural repair processes, and increasing collagen content, underscoring its multifunctional cosmetic potential. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

In Vivo

An in vivo study using excision models to evaluate the effect of topical cranberry extract application.

See journal record

The extract demonstrably supports the skin's natural repair functions, showing significant acceleration in wound contraction. It also effectively increases tissue hydroxyproline content, directly correlating to a boost in collagen for improved skin structure.

Research Study

Research investigating the extract's capacity to mitigate oxidative damage and systemic inflammation.

See journal record

This paper validates the profound free-radical scavenging capacity of the extract's constituent polyphenols. This mechanism underpins its function as a powerful antioxidant active for protecting skin from environmental damage and associated signs of aging.

Clinical

A randomized controlled trial on the effects of sustained cranberry polyphenol exposure on skin health.

See journal record

The study concluded that the extract effectively helps soothe skin by reducing UVB-induced redness (erythema). It also provides a measurable improvement in gross skin elasticity, supporting its use in firming and skin-rejuvenating formulations.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this hydroglycerin stock.

Bulk composition at fixed 5% Vaccinium Macrocarpon Fruit Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-VAM-W1-MBS4-5PCT-001).

Water · 58.737% Propanediol · 24.474% Glycerin · 9.789% Vaccinium Macrocarpon Fruit Extract · 5% Linatural™ MBS-4 · 2%
Water
CAS7732-18-5
Solvent
58.737%
Propanediol
CAS504-63-2
Humectant / solubilizer
24.474%
Glycerin
CAS56-81-5
Humectant carrier
9.789%
Vaccinium Macrocarpon Fruit Extract
CASContact for COA
Active botanical extract (triterpene-rich)
5%
Linatural MBS-4
Multifunctional preservative
2%
Inside Linatural MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (this stock)
0.5%–10%
pH compatibility
4.5 – 5.1 (stock target; finished-formula pH window per stability data)
Solubility
Highly water-soluble; easily incorporated into aqueous phase or final cool-down phase.
Temperature
Process below 40°C; store final product in light-protected packaging at 15–25°C due to heat and light sensitive actives.
Incompatibilities
Strong oxidizing agents, alkaline environments (pH >7.0).
Pairs well with
Water + Propanediol + Glycerin, Hydroglycerin carrier systems.
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs

Documentation

SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.

Need something different?
Custom extract loading, alternate carriers, bulk sizing, or a regulatory packet - reach out and we’ll quote.
Compliance & safety

The fine print, in plain English.

What it’s for
Widely used botanical ingredient in cosmetic formulations.
Claims guidance
Claims guidance is supported by strong evidence for skin care applications, including improving skin elasticity, reducing UVB-induced erythema, accelerating natural repair processes, and increasing collagen content. Can be positioned for anti-aging, firming, soothing, and protective skin care benefits.
Storage
  • Store tightly closed, protected from light and heat.
  • Refrigeration optional for extended shelf life per TDS.
  • Aqueous botanical - monitor for color shift over time.
Regulatory
  • Finished-product INCI lists components in descending order per the selected variant deck.
  • Cosmetic function: antioxidant, skin conditioning agent
  • Full blend composition disclosed on SDS/TDS (FL-VAM series).
  • Competitor offerings include COSMOS-certified versions, demonstrating the botanical's potential to meet natural and organic cosmetic standards.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for intended cosmetic use when properly incorporated.
Handling
Formulation stability is critical; efficacy is pH-dependent, with degradation in alkaline conditions. Process below 40°C, store final product in light-protected packaging at 15–25°C. Avoid strong oxidizing agents and pH above 7.0.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

500 g
$165.00
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