Tripeptide-10 Citrulline cosmetic peptide suspension · peptide found in Decorinyl-class actives™ trade reference / decorin-mimetic fibrillogenesis peptide · choose base, strength, and preservation
Tripeptide-10 Citrulline is a biomimetic peptide found in Decorinyl-class actives that targets collagen fibrillogenesis to restore skin suppleness and elasticity; Formulate Labs supplies Tripeptide-10 Citrulline only — we do not sell or represent Decorinyl.
Lys-Asp-Ile-Cit decorin mimic · CAS 117933-89-8
Tripeptide-10 Citrulline (sequence: Lys-Asp-Ile-Cit-NH2) is a targeted biomimetic tetrapeptide engineered to replicate the function of decorin, a naturally occurring leucine-rich proteoglycan that degrades in aging skin. By binding directly to collagen fibrils, this peptide specifically regulates fibrillogenesis to ensure uniform diameter, regular spacing, and heightened structural cohesion, thereby restoring skin suppleness, resilience, and elasticity in mature profiles.
Market context: — Tripeptide-10 Citrulline stands as a key active in the cosmetic market, with similar peptides found in competitor formulations like Decorinyl® (Lipotec/Lubrizol) for collagen organization, Trylagen® (Lubrizol) for multi-functional anti-aging, and Cosroma® T10-C (COSROMA) for enhancing glue fiber stability. Formulate Labs supplies Tripeptide-10 Citrulline as the pure INCI active and does not sell or represent these supplier-branded SKUs.
Formulate Labs offers Tripeptide-10 Citrulline in highly soluble suspensions across our Glycerin/Water and Sea Kelp Bioferment carriers, ensuring seamless dispersion into aqueous phases and simplifying integration for a recommended 0.01% to 0.05% active peptide in final formulations.
Hair-care note: unlike dermal-papilla or DEJ-anchoring peptides, Tripeptide-10 Citrulline has no primary hair application - follicle growth and keratin shaft structure do not depend on collagen fibrillogenesis. Target facial and body firming skincare.*
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Tripeptide-10 Citrulline is the INCI name for the active ingredient; trade names such as Decorinyl refer to supplier-branded actives, which Formulate Labs does not sell or represent.
Tripeptide-10 Citrulline's efficacy in collagen organization and skin rejuvenation is supported by robust scientific research, including peer-reviewed studies that validate its mechanism as a decorin-mimetic peptide found in Decorinyl-class actives. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
In vitro and in vivo testing confirmed the peptide regulates collagen fibrillogenesis and increases skin suppleness.
A 60-day randomized controlled trial demonstrating significant anti-wrinkle efficacy and improved skin microtopography.
Review validating decorin-like tetrapeptide mechanisms for collagen fiber organization and cohesion.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the TP-10 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
