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Peptide · Aqueous Suspension · Cosmetic Grade

Tripeptide-10 Citrulline

TP-10 cosmetic peptide suspension · choose base, strength, and preservation

Tripeptide-10 Citrulline is H-Lys-Asp-Ile-Cit-NH2 (PubChem CID 90479646, CAS 960531-53-7, formula C22H42N8O7, 530.6 g/mol). Puig and colleagues described a decorin-like tetrapeptide under this INCI name in 2008. Formulate Labs supplies the peptide as a cosmetic raw material.

  • Two bases, two strengths, four preservation options - 10 recipes total, all made-to-order
  • Cosmetic-grade Tripeptide-10 Citrulline · CAS 960531-53-7 · MW 530.6 g/mol
  • COA + SDS + TDS included with every batch · cold-chain optional on request
Base: Glycerin Suspension
Carrier: our single-origin Sea Kelp Bioferment. View material
Strength: 0.2% TP-10
Preservation: Linatural™ MBS-4 INCI breakdown
35% glycerin in water. Selectable preservative; broadest compatibility across personal-care formats. Preserved with Linatural™ MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this suspension, ordered by %)
Water, Glycerin, Propanediol, Tripeptide-10 Citrulline, Ethylhexylglycerin, Benzoic Acid
1
Cosmetic grade
Solid-phase synthesis
COA & SDS
Every single batch
Two carriers
Glycerin or bioferment
Specifications

Everything you need on the technical data sheet.

Peptide INCI
Tripeptide-10 Citrulline
CAS Number
960531-53-7
Molecular Wt
530.6 g/mol
Appearance
Clear, colorless aqueous fluid
pH
4.5 – 5.1
Use Rate
5% (1X)
Add At
Cool-down, ≤ 40 °C
Shelf Life
12–18 mo room temp
18–24 mo refrigerated
Tripeptide-10 Citrulline illustration H-Lys-Asp-Ile-Cit-NH2 · CAS 960531-53-7
The peptide

Tripeptide-10 Citrulline

Tripeptide-10 Citrulline is a synthetic tetrapeptide. PubChem CID 90479646 records the sequence as H-Lys-Asp-Ile-Cit-NH2, molecular formula C22H42N8O7, molecular weight 530.6 g/mol, and CAS 960531-53-7.

Puig, Garcia Anton, and Mangues, International Journal of Cosmetic Science, 2008, reported an in vitro collagen fibrillogenesis result for a tetrapeptide carrying this INCI name. That paper is not a clinical trial of the suspension sold here. Formulate Labs supplies Tripeptide-10 Citrulline as a cosmetic raw material in glycerin/water or Sea Kelp Bioferment. Confirm CAS 960531-53-7 on the lot certificate of analysis before relying on it for a specification.

Identity source: PubChem CID 90479646. In vitro paper: Puig et al., International Journal of Cosmetic Science, 2008.

530.6
g/mol (PubChem CID 90479646)
4
residues, H-Lys-Asp-Ile-Cit-NH2
C22
H42N8O7
2
carrier options on this page
Ingredient deck assessment

What this material is and isn’t.

Vegan
Synthetic peptide, no animal-derived inputs
Non-GMO
Solid-phase synthesis, not biotech-derived
Cruelty-free
No animal testing in our process
Kosher-suitable
Ingredient deck assessed Kosher-suitable
Halal-suitable
Ingredient deck assessed Halal-suitable

These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Fibrillogenesis quality for firming skincare - not hair care.

Recorded tetrapeptide identity
PubChem CID 90479646 lists H-Lys-Asp-Ile-Cit-NH2, CAS 960531-53-7, formula C22H42N8O7, 530.6 g/mol.
2008 in vitro paper
Puig, Garcia Anton, and Mangues, International Journal of Cosmetic Science, 2008, reported an in vitro collagen fibrillogenesis result for this INCI name. That paper is not a clinical trial of this suspension.
Supplied as a suspension
Aqueous glycerin/water or Sea Kelp Bioferment, at the strengths listed on this page.
Cosmetic raw material
For formulation into finished topical products. Confirm CAS 960531-53-7 on the lot certificate of analysis.

Tripeptide-10 Citrulline is the INCI name for the active ingredient; trade names such as Decorinyl refer to supplier-branded actives, which Formulate Labs does not sell or represent.

Published research

Peer-reviewed literature for due diligence.

Puig, Garcia Anton, and Mangues, International Journal of Cosmetic Science, 2008, reported in vitro collagen-fibril results for a tetrapeptide with the INCI name Tripeptide-10 Citrulline. Chemical identity on this page is PubChem CID 90479646, CAS 960531-53-7, 530.6 g/mol. That paper is not a clinical trial of this suspension. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

2008
Peer-reviewed
International Journal of Cosmetic Science

A new decorin-like tetrapeptide for optimal organization of collagen fibres

Puig A, et al.

In vitro collagen fibrillogenesis screen. The abstract reports more uniform fibril diameter for the INCI named Tripeptide-10 Citrulline. This is not a finished-product clinical trial.

2017
Clinical Study
Journal of Cosmetic Dermatology

The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3 in Chinese subjects

Raikou V, et al.

A 60-day randomized controlled trial demonstrating significant anti-wrinkle efficacy and improved skin microtopography.

2017
Review Article
Cosmetics

Topical Peptide Treatments with Effective Anti-Aging Results

Schagen SK

Review validating decorin-like tetrapeptide mechanisms for collagen fiber organization and cohesion.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this suspension.

This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the TP-10 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.

Glycerin · 35% Tripeptide-10 Citrulline · 0.2% Linaturalâ„¢ MBS-4 · 2% Water · 62.8%
Glycerin
CAS56-81-5
Humectant carrier
35%
Tripeptide-10 Citrulline
CAS960531-53-7
Active peptide
0.2%
Linatural™ MBS-4
Multifunctional preservative
2%
Inside Linatural™ MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Water
CAS7732-18-5
Solvent (balance)
62.8%
Formulation guide

Built for chemists who sweat the details.

Typical use rate
5% of the 0.2% (1X) suspension (industry recommended); 0.5% of the 2% (10X) lab concentrate for the same in-formula peptide level of approximately 0.01%
Solubility
Highly water-soluble
pH compatibility
5.0 to 6.5
Add at
Cold process formulation (below 50°C / 122°F)
Mixing
Disperses seamlessly into aqueous phases
Avoid
Strong bases, highly acidic environments, repeated freeze-thaw cycles
Pairs well with
Pairs well with Tripeptide-1 and other collagen-boosting peptides.
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs

Documentation

SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.

Need something different?
Custom concentrations, an alternative carrier, allergen-free preservation, COA-on-file, or a regulatory packet for a specific market - reach out and we’ll quote.
Compliance & safety

The fine print, in plain English.

What it’s for
Cosmetic raw material for leave-on skincare only - advanced anti-aging, firming, and restructuring serums and creams for mature or sun-damaged skin where decorin-mimetic fibrillogenesis support is intended. Not for hair or scalp products - collagen fibril assembly is not a primary follicle pathway. Not a finished consumer product; not for ingestion, injection, or unsupervised topical use outside a formulated finished product.
Claims guidance
Cosmetic structure / function language only (e.g. supports a firmer-looking finish, supports a more supple appearance, supports the look of cohesive skin structure). Avoid decorin drug language (“repairs collagen fibrils,” “treats skin laxity,” “replaces Decorinyl™”). Do not imply we sell or represent the Decorinyl trade name - we supply the INCI peptide only. Do not position in hair care - no primary follicle mechanism. Downstream finished-product claims must be substantiated by the brand.
Storage
  • Store between 2-25 °C in original sealed container away from direct light.
  • Cold storage extends shelf life by ~50% relative to room temperature.
  • Once opened, use within the period stated on the COA.
Regulatory
  • INCI: Tripeptide-10 Citrulline (per ICID and PCPC dictionary).
  • Not classified as hazardous based on currently available information per OSHA HazCom 2012 / GHS.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for the intended use.
  • SDS section 16 disclaimer applies; see the per-recipe SDS for the full classification.
Sensitivity
Tripeptide-10 Citrulline is generally well-tolerated in cosmetic use at the rates above; the supplier’s HET-CAM and AMES studies on the peptide indicate non-irritating and non-mutagenic behavior at industry-standard concentrations. The peptide is light-sensitive: store and ship in opaque containers, and avoid prolonged exposure to direct sunlight in finished formulations. Avoid prolonged contact with strong oxidisers, sustained heat above 50 °C, high shear after incorporation, and finished-formula pH outside 5.0–6.5 - any of these can hydrolyze the peptide and reduce in-formula activity. Patch-test finished formulations per standard cosmetic protocol.
Questions
Documentation, regulatory, custom recipes, COA-on-file requests, or anything else - email materials@formulatelabs.ai and we’ll route to the right person.
1 kg
$900.00
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