Tripeptide-1 cosmetic peptide suspension · peptide found in GHK-class actives signal peptide · parent of GHK-Cu & Pal-GHK · choose base, strength, and preservation
Tripeptide-1, a biomimetic matrikine signal peptide found in GHK-class actives, offers advanced skin repair and anti-aging benefits; Formulate Labs supplies Tripeptide-1 only and does not sell GHK.
Gly-His-Lys (GHK, unlipidated) · CAS 72957-37-0
Tripeptide-1 (Glycyl-Histidyl-Lysine) is a biomimetic matrikine signal peptide that functions as a potent cellular messenger in cosmetic science. It stimulates dermal fibroblasts to synthesize essential extracellular matrix (ECM) components, including collagen types I and III, elastin, fibronectin, and glycosaminoglycans. Positioned as a premium anti-aging and skin-repair active, Tripeptide-1 helps detoxify reactive carbonyl species (RCS) and counteract photo-aging, offering superior firming and structural matrix support.
Market context: Tripeptide-1 is a highly sought-after active in the cosmetic raw material market, recognized for its potent anti-aging and skin-repair properties. While some suppliers market Tripeptide-1 under proprietary trade names such as Kollaren™, Aldenine®, or Active Peptide GHK, Formulate Labs explicitly supplies the INCI Tripeptide-1 active only and does not sell or represent these specific supplier-branded SKUs.
Formulate Labs offers Tripeptide-1 in convenient suspension carriers, including Glycerin/Water and Sea Kelp Bioferment. For standard 1,000 ppm (0.1%) suspensions, typical use levels range from 1.0% to 10.0%, while 10,000 ppm (1%) lab concentrates are generally used at 0.1% to 1.0%, allowing for flexible and effective formulation.
We supply bare GHK as a finished aqueous suspension in two carriers — a 35% glycerin / water base for maximum formulation flexibility, or dosed directly into our single-origin Sea Kelp Bioferment — at 0.01% standard or our 10X lab concentrate at 0.1%.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs supplies the INCI Tripeptide-1 active only and does not sell or represent supplier-branded trade-name SKUs such as GHK, Kollaren™, or Aldenine®.
Tripeptide-1 (GHK) is a foundational signal peptide — isolated from human plasma in 1973 — that modulates ECM gene expression, tissue repair, and follicle biology; copper complexation to GHK-Cu is the most researched bioactive form for regeneration (Pickart et al., 2015). These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Landmark review documenting GHK gene-modulating activity, ECM remodeling (Collagen I/III, elastin, decorin, MMP regulation), redensifying anti-aging endpoints, and wound-healing / angiogenesis positioning.
Foundational GHK-Cu wound-remodeling study reporting stimulation of collagen and GAG synthesis — the clinical wound-care basis for cosmetic repair and post-procedure positioning.
Reports tripeptide-copper stimulation of dermal papilla cell proliferation and anti-apoptotic signaling — core in-vitro support for scalp serums and anagen-prolongation positioning.
Recent androgenetic alopecia work leveraging copper-peptide follicular biology — relevant to VEGF/HIF-1alpha angiogenesis and microcirculation positioning around the hair bulb.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the TP-1 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
