Trifolium Pratense Flower Extract · 5% aqueous hydroglycerin stock
Formulate Labs offers a Trifolium Pratense Flower Extract and Acetyl Tetrapeptide-3 complex as a fixed 5% hydroglycerin stock. This potent blend, standardized for key actives like Biochanin A, supports hair follicle vitality and skin matrix integrity, providing a comprehensive solution for cosmetic formulations.
Red Clover (Trifolium pratense) flowers
Botanical Identity: Formulate Labs’ active system combines Trifolium pratense (Red Clover) flower extract with the biomimetic peptide Acetyl Tetrapeptide-3. This botanical extract is standardized for its high concentration of the phytoestrogen Biochanin A. While similar active ingredients may be known by various trade names, Formulate Labs proudly provides this complex under its transparent INCI for flexible formulation, rather than proprietary supplier SKUs.
Dual mechanism: This material offers a dual-action approach to supporting the hair follicle and surrounding skin matrix. The Trifolium pratense flower extract fraction, rich in Biochanin A, acts as a 5-alpha-reductase inhibitor, helping to modulate local DHT levels and prevent hair follicle miniaturization. In synergy, Acetyl Tetrapeptide-3 targets the dermal papilla to stimulate synthesis of key ECM proteins like collagen III and laminin, improving tissue structural integrity and promoting better follicle anchoring.
Use levels: Our Trifolium Pratense Flower Extract and Acetyl Tetrapeptide-3 complex, provided as a 5% hydroglycerin stock, is recommended at 0.5%–5.0% for intensive hair, lash, or scalp serums. Up to 10.0% is suitable for general skin conditioning applications. These levels refer to the final concentration of Formulate Labs’ active complex in your formulation.
Market context: This INCI combination is positioned as a clinically validated, dual-action active for premium, high-margin applications. It leverages a synergistic mechanism, combining phytoestrogen-driven follicle environment modulation with peptide-driven structural reinforcement of the hair anchor. This multi-pathway approach offers a comprehensive solution for promoting the appearance of thicker, fuller hair, appealing to brands seeking evidence-based marketing stories for hair redensification serums, lash/brow enhancers, and scalp anti-aging treatments.
Pricing context: While the Trifolium pratense botanical fraction is a widely available commodity, the high-purity Acetyl Tetrapeptide-3 powder is a premium active, with bulk pricing frequently approaching $14,500 per kilogram. Formulate Labs offers its complete, formulation-ready active complex at $780.00 for a 500 g sample, $1,200.00 for 1 kg, and $16,320.00 for a 17 kg pail ($960.00 / kg).
We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*
This material is offered under its INCI name, Trifolium Pratense Flower Extract and Acetyl Tetrapeptide-3, not under supplier-specific trade names (e.g., Capixyl™).
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.
The cosmetic efficacy of the Trifolium pratense extract and Acetyl Tetrapeptide-3 combination is supported by peer-reviewed literature detailing its impact on hair growth cycles, hair density, and skin structural integrity. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Topical application of the red clover and peptide mixture increased the ratio of anagen phase hair by 13% while decreasing telogen phase hair by 29% over four months, leading to the appearance of fuller hair.
A 24-week clinical trial positioned this botanical-peptide complex as an effective non-pharmaceutical system for improving the look of hair density, performing comparably to 3% minoxidil for visible signs of androgenetic alopecia.
Histological analysis confirmed that red clover isoflavones support the skin's structural matrix, showing increased total collagen density and epidermal thickness in mature skin, contributing to a firmer and more robust skin appearance.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
Bulk composition at fixed 5% Trifolium Pratense Flower Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-TPF-W1-MBS4-5PCT-001).
SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.
Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.
