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Protein · Stabilizing Suspension · Cosmetic Grade

Superoxide Dismutase

Recombinant antioxidant enzyme (SOD)

Recombinant superoxide dismutase in a stabilizing aqueous suspension for antioxidant and photo-stress cosmetic formulas.*

  • Two strengths: 1X standard or 5X lab concentrate · 50 g pack
  • Stabilizing aqueous suspension · refrigerate 2–8 °C
  • Cosmetic INCI: Superoxide Dismutase only · COA + SDS + TDS per strength
Strength: 1X · 0.032% Superoxide Dismutase Full composition
Shipped in a stabilizing aqueous suspension to protect protein integrity and extend shelf life. Refrigerate 2–8 °C; reconstitute/dilute into your finished formula per the formulation guide. See SDS for full composition.
Target pH
5.5 – 7.0
Shelf life (RT · refrigerated)
6–12 mo · 12–24 mo
Cosmetic INCI (finished product)
Superoxide Dismutase

Suspension stabilizers in the shipped bulk are processing aids and are not declared on the finished-product INCI when the material is used as directed. See SDS for details.

1
Cold chain
Ship & store 2–8 °C
COA & SDS
Every batch
Cosmetic grade
Recombinant protein
Specifications

Everything you need on the technical data sheet.

INCI Name
Superoxide Dismutase
CAS #
9054-89-1
Strengths
1X · 5X lab concentrate
Carrier
Aqueous stabilizing suspension
Appearance
Opaque suspension; resuspend before use
pH
5.5 – 7.0
Storage
2–8 °C refrigerated
Shelf Life
6–12 mo RT · 12–24 mo refrigerated
Superoxide Dismutase illustration Superoxide Dismutase · CAS 9054-89-1 · ~32 kDa (Cu/Zn dimer; confirm on COA)
The protein

The radical-scavenging enzyme for photo-stress and antioxidant cosmetic positioning.

Superoxide Dismutase is the first-line enzymatic antioxidant that converts superoxide radicals to oxygen and hydrogen peroxide. We ship recombinant SOD in a cold-chain stabilizing suspension for leave-on antioxidant serums and photo-stress support formulas. Cosmetic use only.*

We ship recombinant SOD in a stabilizing aqueous suspension at two strengths - standard 1X (0.032%) for typical cosmetic dilution workflows, or a 5X lab concentrate (0.16%) when you want five times the protein loading in the same pack. The suspension helps protect the active during refrigerated storage and reduce deterioration - see SDS for composition details.*

Suspension
Shelf-life strategy
2–8 °C
Refrigerated storage
5X
Lab concentrate option
0
Added preservative
Ingredient deck assessment

What this material is and isn’t.

Vegan
Recombinant protein, no animal-derived inputs
Non-GMO
Bioengineered / fermentation-derived where applicable
Cruelty-free
No animal testing in our process
Kosher-suitable
Ingredient deck assessed Kosher-suitable
Halal-suitable
Ingredient deck assessed Halal-suitable
Made & Mixed in USA
US synthesis + US factory

These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications. If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Enzymatic antioxidant positioning*
Published work places SOD at the front of the skin antioxidant cascade that limits superoxide-driven oxidative stress in cosmetic models.
Photo-stress appearance support*
Topical SOD delivery studies report reduced UVB-induced erythema appearance and sunburn-cell counts in human skin (cosmetic photoprotection context, not a sunscreen drug).
Matrix-integrity positioning*
SOD-class enzymes appear in fibroblast literature around MMP-1 downregulation and extracellular-matrix integrity relevant to firmness-positioned serums.
Cold-chain stabilized enzyme INCI*
Finished-product INCI lists Superoxide Dismutase; suspension stabilizers drop from the cosmetic deck when reconstituted per TDS.

* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.

Published research

Peer-reviewed literature for due diligence.

Superoxide Dismutase is the first-line enzymatic antioxidant that converts superoxide radicals to oxygen and hydrogen peroxide. Cosmetic literature covers topical SOD delivery in human UVB models and reviews of SOD use in antioxidant skincare systems. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

2016
Clinical trial
European Journal of Pharmaceutics and Biopharmaceutics

Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin

Chen X, et al.

In ten volunteers, TAT-SOD applied one hour before UVB raised mean minimal erythema dose by about 37% versus vehicle and reduced sunburn-cell counts after 2-MED exposure. The authors attribute the effect to free-radical scavenging, not physical UV blocking.

2022
In vitro
Antioxidants

SOD3 suppresses the expression of MMP-1 and increases the integrity of extracellular matrix in fibroblasts

Kim JH, et al.

Extracellular SOD3 reduced MMP-1 expression and supported extracellular-matrix integrity in fibroblast models, a mechanism relevant to firmness-positioned antioxidant formulas.

2023
Review
Antioxidants

The Applications and Mechanisms of Superoxide Dismutase in Medicine, Food, and Cosmetics

Zheng M, Liu Y, Zhang G, Yang Z, Xu W, Chen Q

Reviews SOD isoforms, mechanisms, and published uses across medicine, food, and cosmetics, including topical antioxidant positioning and delivery challenges for the intact enzyme.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this suspension.

This is the bulk composition as it ships. Updates dynamically when you change the strength above. The active line shows the SOD loading at the selected concentration. Suspension stabilizers in the shipped bulk protect the active during storage and are not declared on the finished-product cosmetic INCI when the protein is reconstituted / diluted into your formula as directed. Full stabilizer identity and concentration are on the SDS.

Suspension stabilizer · 35% Superoxide Dismutase · 0.032% Purified Water · 64.968%
Suspension stabilizer
Salting-out stabilizer (see SDS)
35%
Superoxide Dismutase
CAS9054-89-1
Active protein / peptide
0.032%
Purified Water
CAS7732-18-5
Solvent (balance)
64.968%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (1X)
Dilute the 1X suspension into the finished formula per TDS; start low and confirm in-formula protein level analytically
Typical use rate (5X)
Use about one-fifth the 1X inclusion of the 5X concentrate for the same in-formula protein level
Solubility
Aqueous suspension; dialyze or buffer-exchange to remove suspension stabilizers before certain finished phases (see TDS)
pH compatibility
5.5 – 7.0 (suspension); target finished-formula pH 4.5 – 7.0 per your stability data
Add at
Cool-down phase, <= 40 C after reconstitution / dialyzation
Storage (raw)
Refrigerated 2-8 C; ship cold; resuspend gently before sampling
Preservation
Unpreserved suspension - finished formula must include appropriate preservation
Pairs well with
Hyaluronic acid, niacinamide, panthenol, copper tripeptide-1, centella, sea kelp bioferment

Documentation

SDS + TDS are issued per strength. Links swap when you change concentration above. COA is batch-specific and ships with the order.

Need something different?
Custom concentrations, bulk sizing, COA-on-file, or a regulatory packet - reach out and we’ll quote.
Compliance & safety

The fine print, in plain English.

What it’s for
Cosmetic raw material - leave-on and rinse-off skincare at the use rates in the formulation guide. Reconstitute / dilute the suspension per TDS before incorporation. Not a finished consumer product.
Claims guidance
Cosmetic structure / function language only. Do not make therapeutic claims (treats sunburn medically, prevents skin cancer, drug-level photoprotection, heals wounds). Downstream finished-product claims must be substantiated by the brand.
Storage
  • Store refrigerated at 2–8 °C in original sealed container.
  • Protect from light; do not freeze.
  • Room-temperature excursions shorten shelf life; see TDS for opened-vial guidance.
Regulatory
  • Finished-product INCI: Superoxide Dismutase (suspension processing aids not declared when used as directed).
  • Full suspension composition, including stabilizer identity, is disclosed on the SDS.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for the intended use when properly reconstituted.
Handling
Protein suspensions require gentle handling and cold-chain discipline. Reconstitute per TDS; avoid prolonged agitation or heat. Patch-test finished formulations per standard cosmetic protocol.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

50 g
$425.00
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