Silybum Marianum Fruit Extract · 5% aqueous hydroglycerin stock
Discover Formulate Labs' Silybum Marianum Fruit Extract, a dual-action active supplied as a fixed 5% hydroglycerin stock. Rich in the potent flavonolignan complex silymarin, with its primary component silibinin, this extract offers significant antioxidant defense and acts as a plant-derived retinol alternative, distinguishing itself from raw powders or generic silymarin-rich thistle materials.
Extract of Milk Thistle fruit
Formulate Labs offers Silybum Marianum Fruit Extract (INCI: Silybum Marianum Fruit Extract), derived from Milk thistle. While commonly known through trade names like Silybum marianum seed/fruit powder or silymarin-rich thistle, we focus on providing our standardized INCI material rather than specific supplier SKUs, ensuring consistent cosmetic efficacy.
Dual mechanism: Silybum Marianum Fruit Extract is a dual-function active, primarily offering potent antioxidant protection by neutralizing reactive oxygen species (ROS) and mitigating UV-induced oxidative damage. Cosmetically, it functions as a plant-derived retinol alternative, supporting skin's structural integrity by inhibiting elastase and collagenase, and as a sebum-regulating agent to clarify blemish-prone skin by modulating sebaceous stem cell differentiation and curbing lipid peroxidation.
Use levels: For typical applications, incorporate this 5% hydroglycerin stock at 0.1% – 1.0%. Higher performance can be achieved by scaling up to 5% based on specific formulation needs.
Market context: Silybum Marianum Fruit Extract is a versatile active that effectively competes in both age-support and blemish control categories. It provides a unique, plant-derived alternative to synthetic retinoids, offering a favorable tolerability profile. Market analysis shows competing actives such as Celyscence™-class for senotherapeutics, Silymarin-class for UV photodamage mitigation, and NATpharma™-class emphasizing botanical purity and antioxidant defense.
Pricing context: While public B2B pricing for standardized raw herbal powder (80% silymarin) ranges from $15 – $40 per kg, specific B2B data for highly refined cosmetic-grade hydroglycerin suspensions remains sparse. Formulate Labs' pricing for our optimized cosmetic suspension of Silybum Marianum Fruit Extract reflects its refined quality and consistent performance.
We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*
Formulate Labs provides Silybum Marianum Fruit Extract by INCI name, distinct from market-specific trade names (Silybum marianum seed/fruit powder, silymarin-rich thistle).
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.
Peer-reviewed literature strongly supports the cosmetic efficacy of Silybum Marianum Fruit Extract. Clinical studies have demonstrated its benefits across key areas, including significant anti-wrinkle efficacy as a retinol alternative and its effectiveness in maintaining homeostasis for acne-prone skin by modulating sebaceous processes. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
In a clinical setting, this extract demonstrated significant anti-wrinkle efficacy by stimulating collagen III and hyaluronic acid, performing as a highly tolerable retinol alternative that outperformed bakuchiol.
A long-term study confirmed that topical use helps maintain balance in acne-prone skin by modulating sebaceous stem cell differentiation, leading to a substantial reduction in the appearance of microcomedones.
A large-scale trial involving 4,230 patients validated the extract's excellent safety profile and confirmed its effectiveness in significantly lowering global acne severity grades in a real-world setting.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
Bulk composition at fixed 5% Silybum Marianum Fruit Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-SIM-W1-MBS4-5PCT-001).
SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.
Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.
