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Botanical Extract · Aqueous or Oil · Standard or Concentrated

Fo-Ti Root Extract

Polygonum Multiflorum Root Extract

standard or concentrated hydroglycerin stock of Polygonum Multiflorum Root Extract, rich in polyphenolic stilbenoids like TSG, offers a dual-action botanical active for comprehensive hair and scalp well-aging; known in traditional contexts as Fo-ti or He Shou Wu, we standardize by INCI for transparent and consistent cosmetic performance.

  • Choose aqueous hydroglycerin (base + preservation) or oil macerate (2 carrier oils)
  • Standard or concentrated Polygonum Multiflorum Root Extract loading in every variant
  • COA + SDS + TDS per selected recipe · 1 kg, 5 kg, and 17 kg
Strength: Standard
Stock type: Aqueous hydroglycerin
Base: Water + Propanediol + Glycerin Extract Full composition
Preservation: Linatural™ MBS-4 INCI breakdown
Aqueous stock with water, propanediol, and glycerin carrying the selected extract loading. Balanced humectancy with propanediol solubilization - default for hair growth-supportive and well-aging serums and toners. Preserved with Linatural™ MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this stock, ordered by %)
Water, Propanediol, Glycerin, Propanediol, Polygonum Multiflorum Root Extract, Ethylhexylglycerin, Benzoic Acid
Size: 1 kg Formulation guide
1
Polygonum Multiflorum Root Extract
Stilbenoid-rich extract (TSG, resveratrol, quercetin)
COA & SDS
Every batch
Cosmetic grade
Aqueous hydroglycerin
Specifications

Everything you need on the technical data sheet.

INCI Name
Polygonum Multiflorum Root Extract
CAS
223748-41-2
Common names
Fo-ti · He Shou Wu
Strength
Standard or concentrated extract in hydroglycerin stock
Solubility
Aqueous / water phase
Appearance
Amber to brown aqueous fluid
pH (bulk material)
4.5 – 5.1
Add at
Cool-down < 40–45 °C
Shelf Life
12–18 mo RT · 18–24 mo refrigerated
Cosmetic micro
TAMC < 100 CFU/g · TYMC < 10 CFU/g
polygonum botanical extract - polygonum hydroglycerin stock Traditional botanical, modern science for hair & scalp wellness.
The extract

Polygonum Multiflorum Root Extract: A Dual-Action Botanical for Hair Wellness

Botanical Identity: Polygonum Multiflorum Root Extract is a revered botanical in traditional practices, often recognized by its common names Fo-ti and He Shou Wu. At Formulate Labs, we ensure clarity and precision by offering this ingredient under its standardized INCI name, not by various trade designations or specific supplier SKUs.

Published mechanism (literature, not a drug claim): Independent papers associate Fo-ti root fractions with hair-cycle and pigmentation pathways, including β-catenin / Shh signaling and TSG-linked melanogenesis (MC1R / MITF / tyrosinase). Those citations are due-diligence references. They do not mean this stock is standardized to TSG, and they do not authorize treatment claims for hair loss or gray hair.

Use levels: Typical finished-formula use of this stock is 0.001% to 5.0% as-is in topical cosmetics. Add on cool-down below 40–45 °C. Validate preservation and stability in your chassis.

Market context: Brands use Polygonum Multiflorum Root Extract as a well-aging hair and scalp botanical: appearance of density plus appearance of premature graying, without stacking two synthetic actives. We sell the INCI extract in our hydroglycerin or oil stock. We do not sell a TCM drug, an ingestible He Shou Wu supplement, or an emodin-assayed isolate unless that grade is separately specified and tested.

We ship standard or concentrated extract stock with selectable preservation - ready to meter into finished formulas at the use rates in the formulation guide below.*

2
Standard / concentrated
2
Hydroglycerin bases
4
Preservation options
Aqueous
Water-phase compatible
Ingredient deck assessment

What this material is and isn’t.

Botanical
Root extract; stilbene glycosides (TSG) and polyphenols
Aqueous or oil stock
Hydroglycerin or carrier-oil macerate
Cruelty-free
No animal testing in our process
Cosmetic grade
For professional formulation use

For clarity and regulatory compliance, Formulate Labs refers to this material by its INCI name, Polygonum Multiflorum Root Extract, rather than common trade names (Fo-ti, He Shou Wu).

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Hair-cycle appearance*
Published cosmetic literature associates this root with support for a healthy-looking hair growth cycle. Use as a hair-conditioning botanical in scalp and hair formulas.
Gray-hair appearance*
Stilbenoid fractions such as TSG are studied for melanogenesis pathways. Cosmetic positioning: helps address the appearance of premature graying. Not a hair-color drug claim.
Density appearance*
Formulators use this stock in well-aging hair stories aimed at the look of thinning. We do not claim treatment of androgenetic alopecia or DHT as a drug target.
Scalp well-aging*
A dual cosmetic story for scalp and hair: conditioning, antioxidant support, and appearance of vitality. Structure/function language only.

* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.

Published research

Peer-reviewed literature for due diligence.

Polygonum Multiflorum Root Extract (Fo-ti, He Shou Wu) is documented in botanical and cosmetic literature for hair- and scalp-conditioning stories. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

-
Review
See PubMed record

See linked PubMed record

See journal record

Peer-reviewed reference cited in Deep Research evidence brief.

-
Review
See PubMed record

See linked PubMed record

See journal record

Peer-reviewed reference cited in Deep Research evidence brief.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the extract stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this hydroglycerin stock.

This is the bulk composition as it ships at the selected extract loading. Updates when you change stock type and variant above. Full CAS disclosure is on the SDS/TDS for the selected recipe.

Water · 61.478% Propanediol · 25.616% Glycerin · 10.246% Polygonum Multiflorum Root Extract · 0.66% Linaturalâ„¢ MBS-4 · 2%
Water
CAS7732-18-5
Solvent
61.478%
Propanediol
CAS504-63-2
Humectant / solubilizer
25.616%
Glycerin
CAS56-81-5
Humectant carrier
10.246%
Polygonum Multiflorum Root Extract
CAS223748-41-2
Starting botanical load 3% · modeled extracted solids, not an assay
Active botanical extract (triterpene-rich)
0.66%
Linatural™ MBS-4
Multifunctional preservative
2%
Inside Linatural™ MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (this stock)
0.001% - 5.0%
pH compatibility
4.5 – 5.1 (stock target; finished-formula pH window per stability data)
Solubility
Water-soluble
Temperature
Avoid prolonged exposure to temperatures above 40°C. Incorporate during cool-down phase.
Incompatibilities
Avoid highly alkaline conditions (pH > 7.0) and strong oxidizing agents. May require polymeric stabilizer in high-salt surfactant systems.
Pairs well with
Compatible with Formulate Labs' Water + Propanediol + Glycerin Extract and Hydroglycerin Extract systems.
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs
Standard QC panel
Aqueous: pH, organoleptic, TAMC < 100 CFU/g, TYMC < 10 CFU/g (total counts only). Oil macerate: organoleptic only. Marker assays are not on the default panel.
Need something different?
Custom extract loading, alternate carriers, bulk sizing, or a regulatory packet - reach out and we’ll quote.

Documentation

SDS + TDS are issued per selected recipe. Links swap when you change selections above. A sample COA shows the standard extract QC panel. Lot-specific COAs ship with every order.

Phytochemistry note

We cook cured Fo-ti root powder into the selected hydroglycerin or oil carrier. The root carries stilbene glycosides (including TSG), polyphenols, and related extractable fractions used in hair- and scalp-conditioning stories. This is a whole-root powder extraction - not a solvent isolate and not a TSG-standardized marker extract. Anthraquinones can occur in the botanical; they are not on the default assay panel. Lot identity appears on the COA and TDS.

Quality & claims

Fo-Ti stock: what we sell, how we release it, and the claim line.

Polygonum Multiflorum Root Extract (Fo-ti / He Shou Wu) as a made-to-order cosmetic extract stock - aqueous hydroglycerin or oil macerate, Standard or Concentrated. We cook cured Fo-ti root powder into the selected carrier. Aqueous lots: pH, organoleptic, TAMC < 100 CFU/g, TYMC < 10 CFU/g (total counts only). Oil macerates: organoleptic only. Literature on TSG and hair-cycle pathways is due diligence, not a TSG assay, hair-loss drug claim, or ingestible TCM product.

Download sample Certificate of Analysis
What we sell
A made-to-order cosmetic extract stock in 1 kg, 5 kg, and 17 kg. Choose aqueous hydroglycerin (base + preservation) or, where offered, an oil macerate. Strength is Standard or Concentrated. We sell the INCI extract in our carrier - not a supplier trade-name SKU and not a finished leave-on product.
How it is made
We cook the raw botanical powder into the selected hydroglycerin or oil carrier on our robotic platform, then fill to order. Aqueous stocks ship preserved at the system you select. Oil macerates ship anhydrous (no water-phase preservative). Extracted solids on the composition bar are modeled from the starting botanical load - they are not an HPLC assay.
Standard extract QC
  • Organoleptic (all stocks): appearance, odor, consistency
  • Aqueous only: pH (typical 4.5–5.5 for the selected preservative)
  • Aqueous only: TAMC < 100 CFU/g and TYMC < 10 CFU/g (total counts; no pathogen panel)
  • Oil macerates: organoleptic only - no pH, TAMC, or TYMC
Not on the default panel: marker assays, heavy metals, pesticides, residual solvents, or individual pathogen screens. Ask if you need those quoted.
What we can claim
Cosmetic structure/function language only: skin- or hair-conditioning, antioxidant cosmetic stories, and appearance-based well-aging positioning supported by published literature. INCI, composition, SDS/TDS, and a lot COA. Compatible with intended cosmetic use under FDA cosmetic rules and EU 1223/2009 when the finished formula is properly assessed.
What we cannot claim
No disease, treatment, cure, or prevent claims. No ingestible / TCM drug positioning. No guarantee that published pathways will reproduce in your finished formula. Not certified organic, COSMOS, vegan, kosher, halal, or non-GMO unless a separate certificate is issued. We do not sell this as a dietary supplement. We do not name a vendor or country of origin for the incoming powder on this page.
Documents with the order
SDS and TDS for the selected recipe (links above swap with your selection). Sample COA on this page for the standard QC panel. Lot-specific COA ships with every batch. Custom loading, alternate carriers, or a fuller regulatory packet - email materials@formulatelabs.ai.
What exactly ships?
A bulk cosmetic extract stock in 1 kg, 5 kg, or 17 kg. Aqueous lots use Water + Propanediol + Glycerin or classic hydroglycerin, with a selectable preservation system. Oil macerates (where offered) ship in a carrier oil, unpreserved. Botanical INCI is Polygonum Multiflorum Root Extract (CAS 223748-41-2). The finished-product INCI is the full selected deck in descending order. We sell the INCI extract in our carrier, not a supplier trade-name SKU.
How is it made?
We start from the raw botanical powder and cook it into the selected hydroglycerin or oil carrier on our robotic platform, then fill to order. Aqueous stocks ship preserved at the system you select. Oil macerates ship anhydrous (no water-phase preservative). Extracted solids on the composition bar are modeled from the starting botanical load - they are not an HPLC marker assay.
What is on the COA?
Aqueous: appearance, odor, consistency, pH, TAMC < 100 CFU/g, TYMC < 10 CFU/g (total counts only - no pathogen panel). Oil: organoleptic only; no pH, TAMC, or TYMC. The sample COA on this page shows representative passing numbers. Your lot COA carries the real lot number and measurements. Marker assays, heavy metals, pesticides, residual solvents, and individual pathogen screens are not on the default panel. Ask if you need those quoted.
Is this a standardized marker isolate?
No. This is a whole-botanical powder extraction into the selected carrier, not a solvent isolate and not a standardized marker extract unless a separate assay is specified and quoted. Composition percentages for extracted solids are modeled from starting botanical load.
Where is the botanical from, and is the stock certified?
Stock is manufactured to order in Fenton, MO. Incoming botanical powder varies by lot. We do not list a vendor or country of origin on this page. The finished extract stock is not certified organic, COSMOS, vegan, kosher, halal, or non-GMO unless a separate certificate is issued. No fragrance is added. Full deck disclosure is on the SDS for the selected recipe.
What can we claim on a finished formula?
Cosmetic structure/function language only: skin- or hair-conditioning, antioxidant cosmetic stories, and appearance-based well-aging positioning. Published literature is due diligence, not finished-product claim substantiation. Do not claim diagnosis, treatment, cure, or prevention of disease. Do not position this as an ingestible, TCM drug, or dietary supplement.
Lead time and shelf life?
Made to order on our robotic platform. Aqueous target shelf life is 12–18 months at room temperature, 18–24 months refrigerated, preservative-dependent. Oil macerates are similar unopened ranges; protect from light and heat. Use-by on the lot COA governs the batch you receive.
What powder goes in?
Cured Fo-ti root powder (Polygonum multiflorum / He Shou Wu). It is a whole-root powder, not a TSG-standardized or emodin-reduced cosmetic isolate. Incoming powder identity can vary by lot. The finished extract stock is not certified organic or kosher.
Is this standardized to TSG or emodin-reduced?
No. We cook the whole cured root powder into the selected carrier. Composition percentages for extracted solids are modeled from starting botanical load, not an HPLC marker assay. Anthraquinones (including emodin) can occur in this botanical. We do not claim emodin-reduced or hepatotoxin-free.
Can we say it grows hair or reverses gray?
No. Cosmetic language only: hair conditioning, antioxidant, helps address the appearance of thinning and premature graying, well-aging scalp/hair. Do not claim treatment of alopecia, restoration of hair color as a drug, or internal / hepatoprotective TCM use. Published pathway papers are not finished-product claim substantiation.
Compliance & safety

The fine print, in plain English.

What it’s for
Cosmetic raw material for hair and scalp care - the appearance of thinning and premature graying, plus general hair-conditioning and antioxidant stories. Not a finished consumer product and not for ingestion.
Claims guidance
Can: hair conditioning agent; antioxidant; helps address the appearance of thinning and premature graying; well-aging scalp/hair positioning. Cannot: treat or reverse alopecia; restore hair color as a drug; hepatoprotective or TCM medical claims; ingestible He Shou Wu; “emodin-free” or “hepatotoxin-free” unless that grade is specified and assayed. Literature citations are not FDA claim substantiation for your brand.
Storage
  • Store tightly closed, protected from light and heat.
  • Refrigeration optional for extended shelf life per TDS.
  • Aqueous botanical - monitor for color shift over time.
Regulatory
  • INCI: Polygonum Multiflorum Root Extract (CAS 223748-41-2, CosIng). Finished-product INCI lists the full selected deck in descending order.
  • Cosmetic function: hair conditioning agent, antioxidant.
  • Full blend composition on SDS/TDS (FL-PMR series). Sample COA on this page; lot COA ships with the order.
  • The raw botanical can contain anthraquinones (including emodin). We do not assay anthraquinones on the standard extract panel. Ask if you need a specified incoming grade or extra testing.
  • Intended cosmetic use under FDA cosmetic rules and EU 1223/2009 when properly incorporated and assessed.
Handling
Topical cosmetic raw material. Add below 40–45 °C. Avoid prolonged heat and highly alkaline conditions (pH > 7.0). Patch-test finished formulas. Keep out of unsupervised consumer use as a bulk stock.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

1 kg
$149.00
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