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Botanical Extract · Aqueous or Oil · Standard or Concentrated

Perilla Leaf Extract

Perilla Frutescens Leaf Extract

Introducing Formulate Labs' Perilla Leaf Extract, a standard or concentrated hydroglycerin stock harnessing key actives like rosmarinic acid, luteolin, and apigenin for advanced cosmetic formulations. Differentiate between 'Perilla' or 'Shiso' and our specific INCI ingredient, Perilla Frutescens Leaf Extract.

  • Choose aqueous hydroglycerin (base + preservation) or oil macerate in MCT, sunflower, jojoba, or squalane
  • Standard or concentrated loading in every variant. Oil stocks are unpreserved.
  • COA + SDS + TDS per selected recipe · 1 kg, 5 kg, and 17 kg
Strength: Standard
Stock type: Aqueous hydroglycerin
Base: Water + Propanediol + Glycerin Extract Full composition
Preservation: Linatural™ MBS-4 INCI breakdown
Aqueous stock with water, propanediol, and glycerin carrying the selected extract loading. Balanced humectancy with propanediol solubilization - default for sensitive, reactive, or barrier-compromised skin serums and toners. Preserved with Linatural™ MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this stock, ordered by %)
Water, Propanediol, Glycerin, Propanediol, Perilla Frutescens Leaf Extract, Ethylhexylglycerin, Benzoic Acid
Size: 1 kg Formulation guide
1
Key Actives
Rosmarinic Acid, Luteolin, Apigenin
COA & SDS
Every batch
Cosmetic grade
Aqueous hydroglycerin
Specifications

Everything you need on the technical data sheet.

INCI Name
Perilla Frutescens Leaf Extract
Common names
Perilla · Shiso Leaf Extract
Strength
Standard or concentrated extract in hydroglycerin stock
Solubility
Aqueous / water phase
Appearance
Amber to brown aqueous fluid
pH (bulk material)
4.5 – 5.1
Add at
Cool-down < 40–45 °C
Shelf Life
12–18 mo RT · 18–24 mo refrigerated
perilla botanical extract - perilla hydroglycerin stock Perilla Frutescens Leaf Extract
The extract

The Science Behind Perilla Leaf Extract

Botanical Identity: Perilla Frutescens Leaf Extract is derived from the leaves of the Perilla frutescens plant, commonly known as Perilla or Shiso. At Formulate Labs, we supply the pure INCI name, Perilla Frutescens Leaf Extract, ensuring clarity and consistency for your cosmetic formulations, rather than proprietary supplier SKUs.

Dual mechanism: Perilla Frutescens Leaf Extract functions through potent antioxidant and soothing properties, protecting the skin's structural integrity by neutralizing environmental aggressors and scavenging reactive oxygen species (ROS) while downregulating pro-inflammatory mediators to calm the skin and reduce the appearance of redness. A secondary mechanism involves the inhibition of cellular tyrosinase, supporting applications aimed at improving skin clarity and promoting a more even, radiant skin tone.

Use levels: For optimal efficacy and stability, incorporate Formulate Labs' Perilla Frutescens Leaf Extract at a recommended concentration of 1.0% – 3.0% into your finished cosmetic formulations, remembering this refers to the dosing of our Standard or Concentrated hydroglycerin stock.

Market context: Perilla Frutescens Leaf Extract can be strongly positioned in the B2B market by focusing on three key growth areas: Sustainability and Green Chemistry, Premium Scalp and Microbiome Care, and Soothing Solutions for Sensitive Skin.

We ship standard or concentrated extract stock with selectable preservation - ready to meter into finished formulas at the use rates in the formulation guide below.*

2
Standard / concentrated
2
Hydroglycerin bases
4
Preservation options
Aqueous
Water-phase compatible
Ingredient deck assessment

What this material is and isn’t.

Botanical
Leaf/stem extract; pentacyclic triterpene saponins
Aqueous stock
Hydroglycerin carrier; water phase
Cruelty-free
No animal testing in our process
Cosmetic grade
For professional formulation use

The specific INCI name, Perilla Frutescens Leaf Extract, is used for Formulate Labs' products to distinguish from common trade names (Perilla, Shiso).

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Antioxidant Protection*
Helps protect skin's structural integrity by neutralizing environmental aggressors and scavenging reactive oxygen species.
Soothing & Calming
Supports skin comfort by helping to calm irritation and reduce the appearance of redness for compromised or reactive skin.
Skin Clarity & Radiance
Promotes a more even and radiant skin tone by supporting improved skin clarity and inhibiting melanin synthesis.
Firmness & Barrier Support
Helps shield dermal fibroblasts from UV-induced matrix damage, supporting skin firmness, elasticity, and barrier function.

* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.

Published research

Peer-reviewed literature for due diligence.

Perilla Frutescens Leaf Extract is documented in cosmetic peptide/protein literature. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

-
Review
See PubMed record

See linked PubMed record

See journal record

Peer-reviewed reference cited in Deep Research evidence brief.

DOIPubMed
-
Review
See PubMed record

See linked PubMed record

See journal record

Peer-reviewed reference cited in Deep Research evidence brief.

DOIPubMed

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the extract stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this hydroglycerin stock.

Bulk composition at the selected Perilla Frutescens Leaf Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at the selected loading. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-PFL-W1-MBS4-5PCT-001).

Water · 61.642% Propanediol · 25.684% Glycerin · 10.274% Perilla Frutescens Leaf Extract · 0.4% Linatural™ MBS-4 · 2%
Water
CAS7732-18-5
Solvent
61.642%
Propanediol
CAS504-63-2
Humectant / solubilizer
25.684%
Glycerin
CAS56-81-5
Humectant carrier
10.274%
Perilla Frutescens Leaf Extract
CASContact for COA
Starting botanical load 2% · modeled extracted solids, not an assay
Active botanical extract (triterpene-rich)
0.4%
Linatural™ MBS-4
Multifunctional preservative
2%
Inside Linatural™ MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (this stock)
1.0% – 3.0%
pH compatibility
4.5 – 5.1 (stock target; finished-formula pH window per stability data)
Solubility
Fully water-soluble. Highly compatible with common cosmetic hydroglycerin systems (Water, Propanediol, Glycerin).
Temperature
Withstands short-term heating up to 60–80°C. For optimal potency, add during cool-down below 40°C and protect final formulation from direct UV exposure.
Incompatibilities
Avoid use in highly alkaline systems (pH > 7.0) and with strong oxidizing agents, which can degrade key actives.
Pairs well with
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs
Need something different?
Custom extract loading, alternate carriers, bulk sizing, or a regulatory packet - reach out and we’ll quote.

Documentation

SDS + TDS are issued per selected recipe. Links swap when you change selections above. A sample COA shows the standard extract QC panel (pH, organoleptic, TAMC/TYMC). Lot-specific COAs ship with every order.

Safety Data Sheet (SDS)
16-section GHS · aqueous extract stock
Technical Data Sheet (TDS)
Composition, storage, incorporation guidance
Certificate of Analysis (sample)
pH · organoleptic · TAMC < 100 · TYMC < 10 CFU/g
Phytochemistry note

We cook the raw botanical powder into the selected carrier. The botanical carries polar phenolics, flavonoid glycosides, and related extractable fractions. Those markers support antioxidant and skin-conditioning cosmetic stories. This is not a solvent isolate or a standardized marker extract. Lot identity appears on the COA and TDS.

Quality & claims

Quality, process, and what we will (and will not) claim.

This is a ready-to-use cosmetic extract stock, not a finished consumer product and not a standardized marker isolate. We cook the raw botanical powder into the selected hydroglycerin or oil carrier. Aqueous lots are released on pH, organoleptic, TAMC, and TYMC (total counts only). Oil macerates are released on organoleptic only. A sample COA is on this page; the lot-specific COA ships with the order.

Download sample Certificate of Analysis
What we sell
A made-to-order cosmetic extract stock in 1 kg, 5 kg, and 17 kg. Choose aqueous hydroglycerin (base + preservation) or, where offered, an oil macerate. Strength is Standard or Concentrated. We sell the INCI extract in our carrier - not a supplier trade-name SKU and not a finished leave-on product.
How it is made
We cook the raw botanical powder into the selected hydroglycerin or oil carrier on our robotic platform, then fill to order. Aqueous stocks ship preserved at the system you select. Oil macerates ship anhydrous (no water-phase preservative). Extracted solids on the composition bar are modeled from the starting botanical load - they are not an HPLC assay.
Standard extract QC
  • Organoleptic (all stocks): appearance, odor, consistency
  • Aqueous only: pH (typical 4.5–5.5 for the selected preservative)
  • Aqueous only: TAMC < 100 CFU/g and TYMC < 10 CFU/g (total counts; no pathogen panel)
  • Oil macerates: organoleptic only - no pH, TAMC, or TYMC
Not on the default panel: marker assays, heavy metals, pesticides, residual solvents, or individual pathogen screens. Ask if you need those quoted.
What we can claim
Cosmetic structure/function language only: skin- or hair-conditioning, antioxidant cosmetic stories, and appearance-based well-aging positioning supported by published literature. INCI, composition, SDS/TDS, and a lot COA. Compatible with intended cosmetic use under FDA cosmetic rules and EU 1223/2009 when the finished formula is properly assessed.
What we cannot claim
No disease, treatment, cure, or prevent claims. No ingestible / TCM drug positioning. No guarantee that published pathways will reproduce in your finished formula. Not certified organic, COSMOS, vegan, kosher, halal, or non-GMO unless a separate certificate is issued. We do not sell this as a dietary supplement. We do not name a vendor or country of origin for the incoming powder on this page.
Documents with the order
SDS and TDS for the selected recipe (links above swap with your selection). Sample COA on this page for the standard QC panel. Lot-specific COA ships with every batch. Custom loading, alternate carriers, or a fuller regulatory packet - email materials@formulatelabs.ai.
What exactly ships?
A bulk cosmetic extract stock in 1 kg, 5 kg, or 17 kg. Aqueous lots use Water + Propanediol + Glycerin or classic hydroglycerin, with a selectable preservation system. Oil macerates (where offered) ship in a carrier oil, unpreserved. Botanical INCI is Perilla Frutescens Leaf Extract. The finished-product INCI is the full selected deck in descending order. We sell the INCI extract in our carrier, not a supplier trade-name SKU.
How is it made?
We start from the raw botanical powder and cook it into the selected hydroglycerin or oil carrier on our robotic platform, then fill to order. Aqueous stocks ship preserved at the system you select. Oil macerates ship anhydrous (no water-phase preservative). Extracted solids on the composition bar are modeled from the starting botanical load - they are not an HPLC marker assay.
What is on the COA?
Aqueous: appearance, odor, consistency, pH, TAMC < 100 CFU/g, TYMC < 10 CFU/g (total counts only - no pathogen panel). Oil: organoleptic only; no pH, TAMC, or TYMC. The sample COA on this page shows representative passing numbers. Your lot COA carries the real lot number and measurements. Marker assays, heavy metals, pesticides, residual solvents, and individual pathogen screens are not on the default panel. Ask if you need those quoted.
Is this a standardized marker isolate?
No. This is a whole-botanical powder extraction into the selected carrier, not a solvent isolate and not a standardized marker extract unless a separate assay is specified and quoted. Composition percentages for extracted solids are modeled from starting botanical load.
Where is the botanical from, and is the stock certified?
Stock is manufactured to order in Fenton, MO. Incoming botanical powder varies by lot. We do not list a vendor or country of origin on this page. The finished extract stock is not certified organic, COSMOS, vegan, kosher, halal, or non-GMO unless a separate certificate is issued. No fragrance is added. Full deck disclosure is on the SDS for the selected recipe.
What can we claim on a finished formula?
Cosmetic structure/function language only: skin- or hair-conditioning, antioxidant cosmetic stories, and appearance-based well-aging positioning. Published literature is due diligence, not finished-product claim substantiation. Do not claim diagnosis, treatment, cure, or prevention of disease. Do not position this as an ingestible, TCM drug, or dietary supplement.
Lead time and shelf life?
Made to order on our robotic platform. Aqueous target shelf life is 12–18 months at room temperature, 18–24 months refrigerated, preservative-dependent. Oil macerates are similar unopened ranges; protect from light and heat. Use-by on the lot COA governs the batch you receive.
Compliance & safety

The fine print, in plain English.

What it’s for
Perilla Frutescens Leaf Extract is a widely used botanical ingredient in cosmetic and personal care products globally, generally considered safe for topical use when formulated according to industry best practices.
Claims guidance
When formulating with Perilla Frutescens Leaf Extract, cosmetic claims can highlight its ability to: Calm & Soothe Skin, Reduce Appearance of Redness, Support Skin Barrier Function, Protect Against Environmental Aggressors, Improve Skin Clarity, and Promote Even Skin Tone.
Storage
  • Store tightly closed, protected from light and heat.
  • Refrigeration optional for extended shelf life per TDS.
  • Aqueous botanical - monitor for color shift over time.
Regulatory
  • Finished-product INCI lists components in descending order per the selected variant deck.
  • Cosmetic function: skin conditioning agent, antioxidant
  • Full blend composition disclosed on SDS/TDS (FL-PFL series).
  • Formulators are responsible for ensuring their final product complies with all regional regulations and should conduct their own safety and stability assessments.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for intended cosmetic use when properly incorporated.
Handling
Formulators are responsible for ensuring their final product complies with all regional regulations and should conduct their own safety and stability assessments. Protect the final formulation from direct UV exposure with opaque packaging to best preserve delicate phenolic and anthocyanin compounds.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

1 kg
$147.00
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