GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration
Reviews GHK biology underlying Pal-GHK cosmetic use: collagen and elastin synthesis, gene modulation, and wound-remodeling pathways in skin.
PT-1 cosmetic peptide suspension · choose base, strength, and preservation
Palmitoyl Tripeptide-1, a potent peptide found in Matrixyl 3000-class actives, significantly stimulates collagen synthesis and reduces wrinkle depth, though Formulate Labs only supplies the pure INCI and does not sell supplier-branded trade names.
Pal-GHK (Palmitoyl-Gly-His-Lys) · CAS 147732-56-7
Palmitoyl Tripeptide-1 is a key peptide revered for its ability to significantly stimulate collagen synthesis and promote extracellular matrix (ECM) repair. Through this mechanism, it actively works to reduce the depth of facial wrinkles and improve overall skin texture, making it a foundational active for advanced anti-aging cosmetic formulations.
Market context: Palmitoyl Tripeptide-1 is a highly sought-after active in the cosmetic industry, frequently positioned by leading suppliers like Sederma (under Matrixyl™ 3000, often blended with Palmitoyl Tetrapeptide-7) as a benchmark for collagen stimulation and anti-wrinkle efficacy. Other market offerings include high-purity solutions from Active Peptide Company and targeted complexes from Brenntag/Uniproma. Formulate Labs provides the pure INCI Palmitoyl Tripeptide-1 raw material, not proprietary trade-name SKUs.
Formulate Labs supplies Palmitoyl Tripeptide-1 in a convenient 0.1% standard glycerin suspension, designed for ease of manufacturing integration and optimal stability. This water-soluble blend ensures efficient incorporation into diverse cosmetic bases, overcoming the dissolution challenges often associated with pure peptide powders.
We supply it on its own at 0.01% standard or 0.1% lab concentrate in glycerin or Sea Kelp Bioferment carriers.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Palmitoyl Tripeptide-1 is the INCI name for this material; Formulate Labs does not sell or represent supplier-branded trade names such as Matrixyl 3000.
Palmitoyl Tripeptide-1 (Pal-GHK) is a matrikine lipopeptide with published work on GHK signaling, collagen gene expression, and Matrixyl 3000 combination systems. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Reviews GHK biology underlying Pal-GHK cosmetic use: collagen and elastin synthesis, gene modulation, and wound-remodeling pathways in skin.
Landmark Matrixyl-family split-face study; while focused on pal-KTTKS, it is the most cited peer-reviewed clinical reference for Sederma matrikine peptide formulas.
Foundational review of matrikine signal peptides including palmitoyl GHK derivatives and their collagen-support mechanism in topical products.
CIR safety assessment explicitly covering tripeptide-1 and its palmitoyl derivative at cosmetic use levels.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the PT-1 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.