Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine cosmetic peptide suspension · peptide found in SYN-TACKS-class actives™ / SYN-TC™ DEJ-anchoring lipopeptide · choose base, strength, and preservation
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is a specialized synthetic signal peptide found in SYN-TACKS-class actives, engineered to reinforce the dermal-epidermal junction and improve skin integrity; Formulate Labs supplies this INCI only and does not sell SYN-TACKS.
Pal-Dab-Thr (SYN-TACKS / SYN-TC core active) · CAS 959610-54-9
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is a highly specialized synthetic signal peptide engineered specifically to target and reinforce the dermal-epidermal junction. By mimicking endogenous cellular communication pathways, it directly stimulates the biosynthesis of critical hemidesmosomal structural proteins, specifically Laminin V, Integrin β4, and Collagens IV, VII, and XVII. In cosmetic science positioning, this broad-spectrum stimulation restructures skin anisotropy, thereby enhancing structural integrity, elasticity, and firmness while visibly reducing the depth of fine lines and wrinkles.
Market context: Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is a key active ingredient associated with competitive offerings such as DSM-Firmenich’s SYN-TACKS®, which is marketed as a dual-peptide blend focused on maximizing dermal-epidermal junction functionality. Formulate Labs supplies the standardized INCI Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine only; we do not sell or distribute these specific competitor trade-name SKUs.
Formulate Labs offers Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine as a high-purity, standardized active ingredient. Our typical offering is supplied as a 0.1% standard glycerin suspension, designed for seamless integration into various cosmetic formulations. This ensures stability, ease of handling, and consistent performance across diverse product applications.
Hair & scalp note: the hair follicle basement membrane zone (BMZ) is structurally identical to skin DEJ — relying on the same Laminin V, Collagen IV, and Collagen VII anchors. Formulators use this peptide in anti-shedding and follicle-fortification serums to strengthen hair-bulb anchoring against mechanical stress — a legitimate hair-care application, not generic density boilerplate.*
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs supplies Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine only; we do not sell supplier trade-name SKUs such as SYN-TACKS.
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is the core DEJ-anchoring lipopeptide in DSM-Firmenich SYN-TACKS and SYN-TC — stimulating Laminin V, Collagen IV/VII, Collagen XVII, and Integrin beta-4 biosynthesis to restore dermal-epidermal junction integrity (DSM-Firmenich, 2010; Bataille et al., 2020). These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Patent filing detailing molecular utility of SYN-class compounds in preventing structural asymmetry and skin sagging.
Topical application of this peptide complex significantly decreases skin folds by stimulating essential basement membrane proteins.
Technical white paper demonstrating in-vitro and in-vivo upregulation of Collagen IV, VII, XVII, and Integrin beta-4.
Peer-reviewed context for structural cosmetic peptides and published efficacy standards in leave-on firming and anti-aging skincare.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the PD-5T loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
