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Peptide · Aqueous Suspension · Cosmetic Grade

Palmitoyl Dipeptide-10

PD-10 cosmetic peptide suspension · choose base, strength, and preservation

Palmitoyl Dipeptide-10 is an advanced lipophilic peptide engineered for enhanced penetration, delivering high-performance anti-aging and DNA-protective benefits to the skin.

  • Two bases, two strengths, four preservation options - 10 recipes total, all made-to-order
  • Cosmetic-grade Palmitoyl Dipeptide-10 · CAS 171263-26-6 · MW ~400 g/mol (approx.)
  • COA + SDS + TDS included with every batch · cold-chain optional on request
Base: Glycerin Suspension
Carrier: our single-origin Sea Kelp Bioferment. View material
Strength: 1% PD-10
Preservation: Linatural MBS-4 INCI breakdown
35% glycerin in water. Selectable preservative; broadest compatibility across personal-care formats. Preserved with Linatural MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this suspension, ordered by %)
Water, Glycerin, Propanediol, Palmitoyl Dipeptide-10, Ethylhexylglycerin, Benzoic Acid
1
Cosmetic grade
Solid-phase synthesis
COA & SDS
Every single batch
Two carriers
Glycerin or bioferment
Specifications

Everything you need on the technical data sheet.

Peptide INCI
Palmitoyl Dipeptide-10
CAS Number
171263-26-6
Molecular Wt
~400 g/mol (approx.)
Appearance
Clear, colorless aqueous fluid
pH
4.5 – 5.1
Use Rate
5-30% (std)
Add At
Cool-down, ≤ 40 °C
Shelf Life
12–18 mo room temp
18–24 mo refrigerated
Palmitoyl Dipeptide-10 (PD-10) molecular illustration Palmitoyl dipeptide-10 (supplier proprietary) · CAS 171263-26-6
The peptide

Palmitoyl Dipeptide-10: Advanced Anti-Glycation and DNA Protection for Youthful Skin

Palmitoyl Dipeptide-10, a synthetic lipophilic peptide identified as Pal-Ala-His and a carnosine-like dipeptide, is engineered for enhanced penetration into the stratum corneum, delivering targeted cosmetic benefits. Positioned as a high-performance active for anti-aging and DNA-protective applications, its primary mechanism involves scavenging reactive oxygen and carbonyl species (ROS/RCS). This dual anti-glycation and antioxidant activity effectively inhibits the Maillard reaction and prevents the formation of advanced glycation end products (AGEs), helping to preserve the integrity of the extracellular matrix, mitigate cellular senescence, and prevent structural protein crosslinking.

Market context: — Palmitoyl Dipeptide-10 is incorporated into various commercially available cosmetic raw materials, each with distinct market positioning. For example, it is a key peptide found in C-Pep Nutecyl-class actives, emphasizing DNA-protective and anti-glycation benefits, as well as in SunPEP Di-100-class actives for antioxidant and skin-firming properties. It is also featured in RLTPep Palmitoyl Dipeptide-10-class actives, promoted for mitochondrial stabilization and free-radical scavenging. Formulate Labs provides this advanced active strictly under its INCI name, Palmitoyl Dipeptide-10, ensuring transparent and flexible formulation solutions; we do not sell or endorse any specific trade-name products.

Formulate Labs makes Palmitoyl Dipeptide-10 available in readily dispersible suspensions, simplifying formulation and handling for chemists. Our standard offering is a 0.1% active concentration in a glycerin solution, providing an easy-to-integrate base. For advanced applications, we also provide higher concentration 1% Lab Concentrates and specialized carriers like Sea Kelp Bioferment, offering versatility to meet diverse formulation needs.

We supply it at 0.1% standard or 1% lab concentrate in glycerin or Sea Kelp Bioferment carriers.

400
g/mol molecular weight (approx.)
2
2 + palmitoyl
2012
commercialised as RLTPep
2
carrier options on this page
Ingredient deck assessment

What this material is and isn’t.

Vegan
Synthetic peptide, no animal-derived inputs
Non-GMO
Solid-phase synthesis, not biotech-derived
Cruelty-free
No animal testing in our process
Kosher-suitable
Ingredient deck assessed Kosher-suitable
Halal-suitable
Ingredient deck assessed Halal-suitable
Made & Mixed in USA
US peptide synthesis + US factory

These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

A peptide with a long cosmetic-science track record.

Palmitoyl Dipeptide-10 Inhibits Glycation
Effectively prevents the formation of advanced glycation end products (AGEs) by inhibiting the Maillard reaction, helping to preserve skin’s youthful elasticity and structure.
Palmitoyl Dipeptide-10 Scavenges ROS/RCS
Acts as a potent scavenger of reactive oxygen and carbonyl species (ROS/RCS), protecting skin from oxidative stress and environmental damage.
Palmitoyl Dipeptide-10 Supports DNA Integrity
Contributes to DNA protection by mitigating cellular senescence and preserving the integrity of the extracellular matrix, fostering healthy skin function.
Palmitoyl Dipeptide-10 for Anti-Aging & Firmness
Supports anti-aging efficacy and improves skin firmness, helping to reduce the visible signs of aging and maintain a youthful skin appearance.

Formulate Labs offers Palmitoyl Dipeptide-10 strictly under its INCI name to ensure transparent and flexible formulation options, and we do not sell or endorse any specific trade-name ingredients.

Published research

Peer-reviewed literature for due diligence.

Palmitoyl Dipeptide-10 is a carnosine-mimetic lipopeptide discussed in anti-glycation and anti-aging cosmetic literature for protecting structural skin proteins. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

2016
Clinical trial
Experimental and Therapeutic Medicine

Instrumental evaluation of anti-aging effects of cosmetic formulations containing palmitoyl peptides, Silybum marianum seed oil, vitamin E and other functional ingredients on aged human skin

Di Salvia A, et al.

Controlled instrumental study of aged skin treated with formulas containing palmitoyl peptides and antioxidant co-actives, reporting wrinkle and elasticity improvements.

2018
Review
International Journal of Toxicology

Safety assessment of tripeptide-1, hexapeptide-12, their metal salts and fatty acyl derivatives, and palmitoyl tetrapeptide-7 as used in cosmetics

Johnson W Jr, et al.

CIR safety review of palmitoyl peptide ingredients used in cosmetic formulas, including tolerability data relevant to lipopeptide actives.

2009
Review
International Journal of Cosmetic Science

Role of topical peptides in preventing or treating aged skin

Lintner K, et al.

Overview of enzyme-inhibitor and signal peptides in cosmetic anti-aging, including anti-glycation and matrix-protection strategies.

2016
Review
Indian Dermatology Online Journal

Topical peptides as cosmeceuticals

Pai VV, et al.

Clinical review of peptide cosmeceuticals covering anti-aging mechanisms and how formulators evaluate published evidence for finished products.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this suspension.

This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the PD-10 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.

Glycerin · 35% Palmitoyl Dipeptide-10 · 1% Linatural™ MBS-4 · 2% Water · 62%
Glycerin
CAS56-81-5
Humectant carrier
35%
Palmitoyl Dipeptide-10
CAS171263-26-6
Active peptide
1%
Linatural MBS-4
Multifunctional preservative
2%
Inside Linatural MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Water
CAS7732-18-5
Solvent (balance)
62%
Formulation guide

Built for chemists who sweat the details.

Typical use rate
1.0%–5.0% for standard 0.01%-0.1% suspensions; adjust proportionally for 1% lab concentrates to achieve desired active concentration.
Solubility
Readily dispersible in water-based phases, including Glycerin/Water and Sea Kelp Bioferment carriers.
pH compatibility
5.0 – 6.5
Add at
Cool-down phase (below 40°C) to prevent thermal degradation.
Mixing
Avoid
Strong oxidizers/reducers, extreme pH levels outside 5.0–6.5. If using Sea Kelp Bioferment carrier, avoid cationic preservatives like Biguanide 20.
Pairs well with
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs

Documentation

SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.

Need something different?
Custom concentrations, an alternative carrier, allergen-free preservation, COA-on-file, or a regulatory packet for a specific market - reach out and we’ll quote.
Compliance & safety

The fine print, in plain English.

What it’s for
Cosmetic raw material - leave-on hair-care formulations (scalp serums, hair tonics, leave-on hair lotions, density-positioned conditioning treatments) at the use rates above; also acceptable in rinse-off cosmetic products and skincare formats where a peptide-based "supports the look of fuller hair" / scalp-comfort positioning is intended. Not a finished consumer product; not for ingestion, injection, or unsupervised topical use outside a formulated finished product.
Claims guidance
Cosmetic structure / function language only (e.g. supports a firmer-looking finish, supports a smoother appearance). Avoid telomere / longevity drug language (“extends telomeres”, “anti-aging gene therapy”, “reverses cellular aging”). Do not make therapeutic claims. The peptide is studied in cosmetic in-vitro and panel work; downstream finished-product claims must be substantiated by the brand.
Storage
  • Store between 2-25 °C in original sealed container away from direct light.
  • Cold storage extends shelf life by ~50% relative to room temperature.
  • Once opened, use within the period stated on the COA.
Regulatory
  • INCI: Palmitoyl Dipeptide-10 (per ICID and PCPC dictionary).
  • Not classified as hazardous based on currently available information per OSHA HazCom 2012 / GHS.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for the intended use.
  • SDS section 16 disclaimer applies; see the per-recipe SDS for the full classification.
Sensitivity
Palmitoyl Dipeptide-10 is generally well-tolerated in cosmetic use at the rates above; the supplier’s HET-CAM and AMES studies on the peptide indicate non-irritating and non-mutagenic behavior at industry-standard concentrations. The peptide is light-sensitive: store and ship in opaque containers, and avoid prolonged exposure to direct sunlight in finished formulations. Avoid prolonged contact with strong oxidisers, sulfuric or phosphoric acids, acetic anhydride, sustained heat above 45 °C, and prolonged exposure to pH > 7.0 - any of these can hydrolyze the peptide and reduce in-formula activity. Patch-test finished formulations per standard cosmetic protocol.
Questions
Documentation, regulatory, custom recipes, COA-on-file requests, or anything else - email materials@formulatelabs.ai and we’ll route to the right person.
1 kg
$825.88
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