NN-1 cosmetic peptide suspension · choose base, strength, and preservation
Nonapeptide-1 is a synthetic cosmetic peptide associated with the melanocortin signaling pathway (PubChem CID 10418849, CAS 158563-45-2, 1,206.5 g/mol). Formulate Labs supplies it as a cosmetic raw material for finished topical products.
Nonapeptide-1 · CAS 158563-45-2
Nonapeptide-1 is a synthetic cosmetic peptide associated with the melanocortin signaling pathway. PubChem CID 10418849 records the sequence as H-Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2, molecular formula C61H87N15O9S, molecular weight 1,206.5 g/mol, and CAS 158563-45-2.
Published research on peptide modulation of the human melanocortin-1 receptor predates the use of Nonapeptide-1 in modern cosmetic formulations. Bonetto and colleagues, Peptides, 2005, reported agonist and antagonist peptides of that receptor. Formulate Labs supplies Nonapeptide-1 as a cosmetic raw material for formulation into finished topical products, in glycerin/water or Sea Kelp Bioferment, at 0.05% or a 0.5% lab concentrate. It is not a drug.
Identity source: PubChem CID 10418849. Receptor paper: Bonetto et al., Peptides, 2005.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs.ai supplies the pure INCI ingredient, Nonapeptide-1, only, and does not sell trade-name SKUs like Melanostatine™ 5, WKPep® Whitenin, or Cosroma® 9N-1.
Nonapeptide-1 is a synthetic cosmetic peptide. Bonetto and colleagues (Peptides, 2005) studied agonist and antagonist peptides of the human melanocortin-1 receptor. That literature is older than this product page. Chemical identity is PubChem CID 10418849. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Reports isolation of agonist and antagonist peptides for the human melanocortin-1 receptor. This is receptor research, not a finished-product clinical trial.
Evaluates melanogenesis inhibition by cosmetic peptide sequences in melanocyte models, with relevance to brightening peptide design and screening methods.
Review of alpha-MSH / MC1R biology that underpins the cosmetic rationale for melanostatine-type antagonist peptides in tone-evening formulas.
Covers cosmetic peptide categories including tone-modulating sequences and the importance of cosmetic (not drug) claim framing for brightening products.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the NN-1 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
