NN-1 cosmetic peptide suspension · choose base, strength, and preservation
Nonapeptide-1 is a biomimetic peptide found in Melanostatine™ 5, WKPep® Whitenin, and Cosroma® 9N-1-class actives that precisely inhibits melanin synthesis for targeted skin brightening; Formulate Labs supplies pure Nonapeptide-1, not trade-name products.
Nonapeptide-1 (melanocyte-stimulating hormone fragment mimic) · CAS 15858-45-2
Nonapeptide-1 is a synthetic, biomimetic peptide functioning as a competitive antagonist of the alpha-melanocyte-stimulating hormone (α-MSH). By binding directly to the melanocortin 1 receptor (MC1R) on the surface of melanocytes, it blocks the upstream signaling cascade that normally activates tyrosinase, effectively inhibiting melanin synthesis at its biological origin. In cosmetic science, Nonapeptide-1 is positioned as a highly targeted, non-cytotoxic skin-brightening active that addresses post-inflammatory hyperpigmentation, melasma, and UV-induced dark spots without compromising overall melanocyte viability.
Market context: — Public B2B market pricing data for cosmetic peptides is sparse, but available wholesale quotes indicate that 98-99% pure Nonapeptide-1 powder and standard 1000 ppm liquid suspensions are readily available. Several prominent trade names utilize Nonapeptide-1, including Melanostatine™ 5 (Lucas Meyer Cosmetics), WKPep® Whitenin (Shenzhen Winkey Technology), and Cosroma® 9N-1 (COSROMA). Formulate Labs provides the pure INCI ingredient, Nonapeptide-1, and does not sell these branded trade-name SKUs.
Formulate Labs supplies Nonapeptide-1 in a stable 0.1% standard glycerin suspension, engineered for optimal integration into cosmetic formulations. This allows formulators to easily incorporate a potent concentration of the peptide, ensuring its targeted skin-brightening efficacy is preserved and delivered effectively in final products.
We supply it at 0.1% standard or 1% lab concentrate in glycerin or Sea Kelp Bioferment carriers.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs.ai supplies the pure INCI ingredient, Nonapeptide-1, only, and does not sell trade-name SKUs like Melanostatine™ 5, WKPep® Whitenin, or Cosroma® 9N-1.
Nonapeptide-1 (Melanostatine) is documented in melanocortin-receptor peptide literature as an alpha-MSH antagonist sequence studied for cosmetic melanogenesis modulation. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Identifies synthetic melanocortin peptides including MC1R antagonists; foundational work for alpha-MSH-blocking cosmetic brightening sequences.
Evaluates melanogenesis inhibition by cosmetic peptide sequences in melanocyte models, with relevance to brightening peptide design and screening methods.
Review of alpha-MSH / MC1R biology that underpins the cosmetic rationale for melanostatine-type antagonist peptides in tone-evening formulas.
Covers cosmetic peptide categories including tone-modulating sequences and the importance of cosmetic (not drug) claim framing for brightening products.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the NN-1 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
