HX-33 cosmetic peptide suspension · choose base, strength, and preservation
Hexapeptide-33 is a multi-functional signal peptide, often found in W3 PEPTIDE-class actives (which Formulate Labs does not sell), designed to modulate epidermal homeostasis for comprehensive wound healing, wrinkle reduction, and skin whitening.
Hexapeptide-33 sequence (supplier proprietary) · CAS 1477324-81-8
Hexapeptide-33 is a synthetic signal peptide specifically engineered to interact with G-Protein-Coupled-Receptors (GPCRs), a key mechanism for modulating epidermal homeostasis. This multi-functional peptide offers a 'Triple-W' efficacy profile, strategically positioning it for advanced cosmetic formulations: stimulating angiogenesis for enhanced wound healing, promoting collagen I synthesis for visible wrinkle reduction, and inhibiting tyrosinase and melanin synthesis for effective skin whitening and anti-pigmentation benefits.
Market context: Hexapeptide-33 is a key peptide often benchmarked against or formulated with other premium tyrosinase-inhibiting or GPCR-modulating peptide complexes like Oligopeptide-68 and Decapeptide-12. While a prominent commercial trade name, W3 PEPTIDE-class actives, also utilizes Hexapeptide-33 for its 'Triple W' mechanism, Formulate Labs explicitly sells Hexapeptide-33 as a standalone INCI ingredient and does not supply or distribute any competitor trade-name SKUs.
Formulate Labs offers Hexapeptide-33 as a standardized INCI raw material, available in a stable 0.1% standard glycerin suspension, ideal for B2B manufacturing. Our focus is on providing high-purity Hexapeptide-33, ensuring reliable integration into your formulations without offering competitor trade-name SKUs.
We supply it as a finished aqueous suspension in glycerin and water or our Sea Kelp Bioferment carrier at 0.2% standard or 2% lab concentrate.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs supplies Hexapeptide-33 as a standardized INCI raw material and does not sell or distribute competitor trade-name SKUs.
Hexapeptide-33 (W3 / Angio-S) appears in peptide-science literature on angiogenic signaling, keratinocyte biology, and cosmetic tolerability testing. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Characterizes a synthetic hexapeptide angiogenic signal in endothelial cell models, supporting the microcirculation and matrix-repair rationale for hexapeptide-33 in skincare.
Validates the safety profile for topical dermal applications, demonstrating an absence of cytotoxicity and primary skin irritation.
Demonstrates melanogenesis inhibition and antioxidant activity suitable for anti-pigmentation and anti-aging cosmetic positioning.
General peer-reviewed context for peptide cosmeceuticals, claim boundaries, and formulation considerations in leave-on skincare.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the HX-33 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
