Grifola Frondosa Extract
Unlock the adaptogenic power of Formulate Labs' Grifola Frondosa Extract, available as a standard or concentrated hydroglycerin stock. Rich in beta-glucans, glycoproteins, and polyphenols, our unbranded INCI material provides comprehensive support for skin health, offering formulation flexibility beyond proprietary trade names.
An adaptogenic mushroom recognized for its rich bioactive compounds.
Botanical Identity: Grifola frondosa extract is a multifactorial cosmetic active derived from an adaptogenic mushroom. Trade Names: Commonly known as Maitake or Hen-of-the-woods, Formulate Labs provides the pure INCI material, not specific supplier SKUs, allowing for flexible and cost-effective innovation.
Dual mechanism: From a cosmetic science perspective, this extract provides comprehensive support for aging or stressed skin. It functions as a powerful antioxidant, neutralizing reactive oxygen species (ROS) to protect against environmental damage and helps preserve skin's structural integrity by inhibiting collagen-degrading MMP-1 while supporting new collagen biosynthesis. Furthermore, its peptide and polysaccharide fractions help soothe the skin by down-regulating inflammatory signaling pathways, providing robust cellular defense against UV-induced stress.
Use levels: For Formulate Labs' hydroglycerin stock, a use level of 1.0% – 5.0% is recommended for standard emulsion efficacy. Purified fractions of Grifola Frondosa Extract have demonstrated biological activity at levels as low as 0.01%.
Market context: Grifola frondosa extract is a key component in several well-known trade-name actives focused on adaptogenic, anti-aging, and skin-firming benefits. Formulate Labs provides the unbranded, pure INCI material, allowing for formulation flexibility and cost-effective innovation.
We ship standard or concentrated extract stock with selectable preservation - ready to meter into finished formulas at the use rates in the formulation guide below.*
Formulate Labs provides the unbranded, pure INCI material, differentiating it from branded trade-name actives (Maitacure, Actifirm, Actifcol, Extrapone® Maitake GW).
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.
The multifaceted benefits of Grifola Frondosa Extract for skin health are supported by scientific research, highlighting its antioxidant, anti-inflammatory, and structural protective properties through various mechanisms. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
This research demonstrates the extract's capacity to soothe compromised skin by suppressing pro-inflammatory cytokine expression in keratinocytes, supporting its use in formulations aimed at reducing visible signs of skin irritation.
This paper highlights the extract's ability to act as a functional antioxidant, preventing stress-induced cellular damage in skin fibroblasts by blocking NF-κB activation, supporting its role in protecting the dermal matrix.
The polysaccharide and glycoprotein fractions in the extract show significant antioxidant activity against UV-induced free radicals while promoting fibroblast proliferation, helping defend skin from photodamage and supporting natural collagen production.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the extract stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
Bulk composition at the selected Grifola Frondosa Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at the selected loading. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-GRF-W1-MBS4-5PCT-001).
SDS + TDS are issued per selected recipe. Links swap when you change selections above. A sample COA shows the standard extract QC panel (pH, organoleptic, TAMC/TYMC). Lot-specific COAs ship with every order.
We cook the raw botanical powder into the selected carrier. The botanical carries polar phenolics, flavonoid glycosides, and related extractable fractions. Those markers support antioxidant and skin-conditioning cosmetic stories. This is not a solvent isolate or a standardized marker extract. Lot identity appears on the COA and TDS.
This is a ready-to-use cosmetic extract stock, not a finished consumer product and not a standardized marker isolate. We cook the raw botanical powder into the selected hydroglycerin or oil carrier. Aqueous lots are released on pH, organoleptic, TAMC, and TYMC (total counts only). Oil macerates are released on organoleptic only. A sample COA is on this page; the lot-specific COA ships with the order.
Download sample Certificate of AnalysisStatements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.
