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Botanical Extract · Aqueous Hydroglycerin · 5% Loading

Maitake Extract

Grifola Frondosa Extract · 5% aqueous hydroglycerin stock

Unlock the adaptogenic power of Formulate Labs' Grifola Frondosa Extract, available as a fixed 5% hydroglycerin stock. Rich in beta-glucans, glycoproteins, and polyphenols, our unbranded INCI material provides comprehensive support for skin health, offering formulation flexibility beyond proprietary trade names.

  • Fixed 5% Grifola Frondosa Extract in Water + Propanediol + Glycerin Extract or Hydroglycerin Extract base
  • Four preservation systems - 8 recipes total, all made-to-order
  • COA + SDS + TDS per base/preservative variant · 500 g to 17 kg
Base: Water + Propanediol + Glycerin Extract Full composition
Preservation: Linatural MBS-4 INCI breakdown
Aqueous stock with water, propanediol, and glycerin carrying 5% botanical extract. Balanced humectancy with propanediol solubilization - default for anti-aging, soothing, and protective serums and toners. Preserved with Linatural MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this stock, ordered by %)
Water, Propanediol, Glycerin, Grifola Frondosa Extract, Propanediol, Ethylhexylglycerin, Benzoic Acid
Size: 500 g Formulation guide
1
Maitake Mushroom
Beta-glucan & Polyphenol-rich Extract
COA & SDS
Every batch
Cosmetic grade
Aqueous hydroglycerin
Specifications

Everything you need on the technical data sheet.

INCI Name
Grifola Frondosa Extract
Common names
Maitake · Hen-of-the-woods
Loading
5% extract in hydroglycerin stock
Solubility
Aqueous / water phase
Appearance
Amber to brown aqueous fluid
pH (bulk material)
4.5 – 5.1
Add at
Cool-down < 40–45 °C
Shelf Life
12–18 mo RT · 18–24 mo refrigerated
grifola botanical extract - grifola hydroglycerin stock An adaptogenic mushroom recognized for its rich bioactive compounds.
The extract

Grifola frondosa: The Adaptogenic Mushroom for Skin Resilience

Botanical Identity: Grifola frondosa extract is a multifactorial cosmetic active derived from an adaptogenic mushroom. Trade Names: Commonly known as Maitake or Hen-of-the-woods, Formulate Labs provides the pure INCI material, not specific supplier SKUs, allowing for flexible and cost-effective innovation.

Dual mechanism: From a cosmetic science perspective, this extract provides comprehensive support for aging or stressed skin. It functions as a powerful antioxidant, neutralizing reactive oxygen species (ROS) to protect against environmental damage and helps preserve skin's structural integrity by inhibiting collagen-degrading MMP-1 while supporting new collagen biosynthesis. Furthermore, its peptide and polysaccharide fractions help soothe the skin by down-regulating inflammatory signaling pathways, providing robust cellular defense against UV-induced stress.

Use levels: For Formulate Labs' hydroglycerin stock, a use level of 1.0% – 5.0% is recommended for standard emulsion efficacy. Purified fractions of Grifola Frondosa Extract have demonstrated biological activity at levels as low as 0.01%.

Market context: Grifola frondosa extract is a key component in several well-known trade-name actives focused on adaptogenic, anti-aging, and skin-firming benefits. Formulate Labs provides the unbranded, pure INCI material, allowing for formulation flexibility and cost-effective innovation.

Pricing context: Public B2B pricing for highly refined, cosmetic-grade Grifola frondosa suspensions is sparse, with bulk nutraceutical-grade powders ranging from $8 to $42 per kilogram. For Formulate Labs' cosmetic-grade quantities, typical pricing is: 500 g (Sample): $143.00; 1 kg: $220.00; 17 kg (Bulk Pail): $3,179.00 ($187.00/kg).

We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*

5%
Fixed extract loading
2
Hydroglycerin bases
4
Preservation options
Aqueous
Water-phase compatible
Ingredient deck assessment

What this material is and isn’t.

Botanical
Leaf/stem extract; pentacyclic triterpene saponins
Aqueous stock
Hydroglycerin carrier; water phase
Cruelty-free
No animal testing in our process
Cosmetic grade
For professional formulation use

Formulate Labs provides the unbranded, pure INCI material, differentiating it from branded trade-name actives (Maitacure, Actifirm, Actifcol, Extrapone® Maitake GW).

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Antioxidant Defense*
Helps neutralize reactive oxygen species (ROS) to protect against environmental damage and oxidative stress.
Supports Skin Firmness*
Aids in preserving skin’s structural integrity by inhibiting collagen degradation and supporting new collagen synthesis.
Soothing & Calming
Helps soothe the skin by down-regulating inflammatory signaling pathways, reducing visible signs of irritation.
Cellular Resilience*
Provides robust cellular defense against environmental stressors, including UV-induced stress and fibroblastic pyroptosis.

* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.

Published research

Peer-reviewed literature for due diligence.

The multifaceted benefits of Grifola Frondosa Extract for skin health are supported by scientific research, highlighting its antioxidant, anti-inflammatory, and structural protective properties through various mechanisms. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

2023
Peer-reviewed
Nutrients, Research and Practice

Anti-inflammatory effect of water extract from Grifola frondosa in lipopolysaccharide-stimulated human keratinocytes

See journal record

This research demonstrates the extract's capacity to soothe compromised skin by suppressing pro-inflammatory cytokine expression in keratinocytes, supporting its use in formulations aimed at reducing visible signs of skin irritation.

2022
Peer-reviewed
Nutrients

Current Progress of Grifola frondosa Polysaccharides in the Prevention and Treatment of Non-Communicable Diseases

See journal record

This paper highlights the extract's ability to act as a functional antioxidant, preventing stress-induced cellular damage in skin fibroblasts by blocking NF-κB activation, supporting its role in protecting the dermal matrix.

2021
Peer-reviewed
Foods

Antioxidant and Anti-Aging Activities of Polysaccharides from Grifola frondosa Mycelium Fermentation

See journal record

The polysaccharide and glycoprotein fractions in the extract show significant antioxidant activity against UV-induced free radicals while promoting fibroblast proliferation, helping defend skin from photodamage and supporting natural collagen production.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this hydroglycerin stock.

Bulk composition at fixed 5% Grifola Frondosa Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-GRF-W1-MBS4-5PCT-001).

Water · 58.737% Propanediol · 24.474% Glycerin · 9.789% Grifola Frondosa Extract · 5% Linatural™ MBS-4 · 2%
Water
CAS7732-18-5
Solvent
58.737%
Propanediol
CAS504-63-2
Humectant / solubilizer
24.474%
Glycerin
CAS56-81-5
Humectant carrier
9.789%
Grifola Frondosa Extract
CASContact for COA
Active botanical extract (triterpene-rich)
5%
Linatural MBS-4
Multifunctional preservative
2%
Inside Linatural MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (this stock)
1.0% – 5.0%
pH compatibility
4.5 – 5.1 (stock target; finished-formula pH window per stability data)
Solubility
Fully water-soluble
Temperature
Add during cool-down phase; avoid prolonged high heat. Store in cool, dark conditions.
Incompatibilities
Avoid extreme pH (strong acids or bases). Sensitive to trace heavy metals (can cause oxidation/discoloration).
Pairs well with
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs

Documentation

SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.

Need something different?
Custom extract loading, alternate carriers, bulk sizing, or a regulatory packet - reach out and we’ll quote.
Compliance & safety

The fine print, in plain English.

What it’s for
A botanical extract generally recognized for cosmetic use globally.
Claims guidance
Skin Care: Anti-aging, soothing, protective, antioxidant, skin firming, improves appearance of firm- and youthful-looking skin, reduces visible signs of skin irritation and sensitivity, protects fibroblasts from environmental stressors. Scalp Care: Soothes a dry, irritated scalp, protects follicles from oxidative stress.
Storage
  • Store tightly closed, protected from light and heat.
  • Refrigeration optional for extended shelf life per TDS.
  • Aqueous botanical - monitor for color shift over time.
Regulatory
  • Finished-product INCI lists components in descending order per the selected variant deck.
  • Cosmetic function: skin conditioning agent, antioxidant, soothing agent
  • Full blend composition disclosed on SDS/TDS (FL-GRF series).
  • Formulators are responsible for ensuring compliance with all local and regional regulations for their specific market.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for intended cosmetic use when properly incorporated.
Handling
Store in cool, dry, and dark conditions to maintain the structural integrity of its bioactive components.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

500 g
$143.00
Added to cart View cart →