Something Exciting is Coming

We're working hard to bring you an amazing new experience. Stay tuned for updates!

Launching 2026
Schedule a Call
Botanical Extract · Aqueous Hydroglycerin · Standard or Concentrated

Canadian Willowherb Extract

Epilobium Angustifolium Flower/Leaf/Stem Extract

Discover the soothing and balancing power of Epilobium Angustifolium. Our standardized extract, featuring key actives like Oenothein B, flavonoids, and phenolic acids, is supplied as a standard or concentrated hydroglycerin stock, distinguishing it from general Canadian Willowherb or Fireweed raw materials.

  • Standard or concentrated Epilobium Angustifolium Flower/Leaf/Stem Extract in Water + Propanediol + Glycerin Extract or Hydroglycerin Extract base
  • Four preservation systems - 8 recipes total, all made-to-order
  • COA + SDS + TDS per base/preservative variant · 1 kg, 5 kg, and 17 kg
Strength: Standard
Base: Water + Propanediol + Glycerin Extract Full composition
Preservation: Linatural™ MBS-4 INCI breakdown
Aqueous stock with water, propanediol, and glycerin carrying the selected extract loading. Balanced humectancy with propanediol solubilization - default for oily, blemish-prone, and sensitive skin serums and toners. Preserved with Linatural™ MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this stock, ordered by %)
Water, Propanediol, Glycerin, Propanediol, Epilobium Angustifolium Flower/Leaf/Stem Extract, Ethylhexylglycerin, Benzoic Acid
Size: 1 kg Formulation guide
1
Oenothein B
Key macrocyclic ellagitannin
COA & SDS
Every batch
Cosmetic grade
Aqueous hydroglycerin
Specifications

Everything you need on the technical data sheet.

INCI Name
Epilobium Angustifolium Flower/Leaf/Stem Extract
Common names
Canadian Willowherb · Fireweed · Willowherb
Strength
Standard or concentrated extract in hydroglycerin stock
Solubility
Aqueous / water phase
Appearance
Amber to brown aqueous fluid
pH (bulk material)
4.5 – 5.1
Add at
Cool-down < 40–45 °C
Shelf Life
12–18 mo RT · 18–24 mo refrigerated
epilobium botanical extract - epilobium hydroglycerin stock Canadian Willowherb · Fireweed
The extract

The Multi-Functional Science of Canadian Willowherb

Botanical Identity: Derived from the resilient *Epilobium Angustifolium* plant, also commonly known as Canadian Willowherb, Fireweed, or simply Willowherb. Our Product: We provide the pure botanical extract, identified by its INCI name Epilobium Angustifolium Flower/Leaf/Stem Extract, distinct from various supplier-specific trade names or branded ingredients.

Dual mechanism: The cosmetic activity of Epilobium Angustifolium Flower/Leaf/Stem Extract is multi-faceted, driven by its rich polyphenol profile, primarily the macrocyclic ellagitannin Oenothein B. It acts as a potent inhibitor of 5-α-reductase, helping to balance surface oils, and suppresses inflammatory pathways by inhibiting lipoxygenase and cyclooxygenases (COX-1 and COX-2) to reduce visible erythema and irritation. Furthermore, it supports the skin's structural matrix by inhibiting matrix metalloproteinases (MMPs) like collagenase, elastase, and hyaluronidase, contributing to the appearance of skin firmness and texture. Additional benefits include direct antioxidant activity against reactive oxygen species (ROS) and antibacterial properties against microbes relevant to blemishes, such as *P. acnes*.

Use levels: For optimal efficacy, particularly for rapid anti-erythema effects, Formulate Labs' standardized hydroglycerin stock is typically incorporated into formulations at a rate of 1.0% to 5.0%. Optimal results are often observed between 1.0% and 3.0%.

Market context: Epilobium Angustifolium Flower/Leaf/Stem Extract is a versatile active competing in the high-performance botanical space. Products in this category are often positioned for rapid anti-irritant effects, with claims around reducing visible redness from chemical or UV exposure. Others emphasize lipid-soluble properties for biomimetic skin barrier support and protection from oxidative stress, while some are aggressively marketed for managing hyperseborrhoea and blemishes through potent anti-androgenic and antimicrobial activity.

We ship standard or concentrated extract stock with selectable preservation - ready to meter into finished formulas at the use rates in the formulation guide below.*

Epilobium Angustifolium Flower/Leaf/Stem Extract delivers multi-faceted cosmetic activity, primarily driven by its rich profile of polyphenols, including the macrocyclic ellagitannin Oenothein B, alongside supportive flavonoids and phenolic acids. This potent peptide addresses key concerns related to skin irritation, blemishes, and overall structural integrity. It functions as a powerful inhibitor of 5-α-reductase, an enzyme critically linked to sebum production, thereby helping to balance surface oils on both skin and scalp. For soothing applications, it actively suppresses inflammatory pathways by inhibiting lipoxygenase and cyclooxygenases (COX-1 and COX-2), leading to a visible reduction in erythema and sensations of irritation. Furthermore, its ability to inhibit matrix metalloproteinases (MMPs) such as collagenase, elastase, and hyaluronidase helps preserve the appearance of skin firmness and texture, supporting the skin’s structural matrix. These actions are complemented by direct antioxidant activity through the neutralization of reactive oxygen species (ROS) and antibacterial properties against microbes like P. acnes, making it exceptionally well-suited for formulations targeting oily, blemish-prone, and sensitive skin.

Market context: Epilobium Angustifolium Flower/Leaf/Stem Extract is a highly competitive, multi-functional active that stands alongside other high-performance botanicals in the market. Actives found in Canadian Willowherb™-class products are often recognized for their rapid anti-irritant effects, specifically reducing visible redness from chemical or UV exposure. The extract found in EPILOBIUM Oléoactif®-class actives, differentiated by a patented oil-based extraction, emphasizes lipid-soluble benefits for barrier reinforcement and moisturization. Meanwhile, the extract found in Seborilys-class actives typically appears in synergistic botanical blends, marketed for aggressive management of hyperseborrhoea and blemishes through potent anti-androgenic and antimicrobial activity. Formulate Labs offers Epilobium Angustifolium Flower/Leaf/Stem Extract as a versatile and standardized raw material, distinct from these branded end-products.

Formulate Labs provides Epilobium Angustifolium Flower/Leaf/Stem Extract in a cosmetic-grade hydroglycerin base, meticulously standardized for its Oenothein B content. This ensures a consistent, high-performance active ingredient, ready for seamless integration into your formulations. Our robust supply chain and quality control guarantee the purity and efficacy required for professional cosmetic development.

We ship standard or concentrated extract stock with selectable preservation - ready to meter into finished formulas at the use rates in the formulation guide below.*

2
Standard / concentrated
2
Hydroglycerin bases
4
Preservation options
Aqueous
Water-phase compatible
Ingredient deck assessment

What this material is and isn’t.

Botanical
Leaf/stem extract; pentacyclic triterpene saponins
Aqueous stock
Hydroglycerin carrier; water phase
Cruelty-free
No animal testing in our process
Cosmetic grade
For professional formulation use

Our product is identified by its INCI name, Epilobium Angustifolium Flower/Leaf/Stem Extract, distinct from various supplier-specific trade names (Canadian Willowherb, Fireweed, Willowherb).

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Soothing & Calming*
Helps to visibly reduce erythema and sensations of irritation by suppressing inflammatory pathways, ideal for sensitive skin.
Blemish & Oil Control
Inhibits 5-α-reductase to balance surface oils and provides antibacterial action against *P. acnes* for clearer-looking skin.
Supports Skin Structure*
Inhibits key matrix metalloproteinases (MMPs) like collagenase and elastase, helping to preserve the appearance of skin firmness and texture.
Antioxidant Protection
Neutralizes reactive oxygen species (ROS), providing direct antioxidant benefits to help protect the skin from environmental stressors.

This product refers to the raw material Epilobium Angustifolium Flower/Leaf/Stem Extract and not to any branded or finished cosmetic products containing this extract.

Published research

Peer-reviewed literature for due diligence.

The efficacy of Epilobium Angustifolium Flower/Leaf/Stem Extract is robustly supported by peer-reviewed scientific literature. Research highlights its diverse activities, including potent antioxidant capacity, anti-inflammatory properties, sebum-regulating effects, and antimicrobial action, validating its multi-functional benefits for cosmetic applications. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

2022
Review
Molecules

Therapeutic Potential of Polyphenols from *Epilobium angustifolium* (Fireweed)

Schepetkin IA, et al.

This review emphasizes the dermocosmetic value of Oenothein B, the extract's primary bioactive, in neutralizing damaging reactive oxygen species and inhibiting COX-1/COX-2 pathways, supporting its role in soothing irritated skin.

2016
Research
Phytotherapy Research

Chemical composition, antioxidative and anti-inflammatory activity of extracts prepared from aerial parts of *Epilobium* species

Granica S, et al.

This study confirms the antibacterial action of the extract's polyphenols and ellagitannins against *P. acnes*, a key factor in blemish-prone skin, and demonstrates potent immunomodulatory activity suitable for calming and rebalancing skin.

2024
Research
Cosmetics

*Epilobium angustifolium* L. Extract as a Multifunctional and Sustainable Active Ingredient for Skin Care Applications

Kurek-Górecka A, et al.

Pharmacological studies validate the extract's effectiveness as a sustainable cosmetic ingredient for managing surface oil and soothing skin, making it an excellent choice for products targeting blemishes, dandruff, and acute redness.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the extract stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this hydroglycerin stock.

Bulk composition at the selected Epilobium Angustifolium Flower/Leaf/Stem Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at the selected loading. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-EAE-W1-MBS4-5PCT-001).

Water · 61.187% Propanediol · 25.495% Glycerin · 10.198% Epilobium Angustifolium Flower/Leaf/Stem Extract · 1.12% Linatural™ MBS-4 · 2%
Water
CAS7732-18-5
Solvent
61.187%
Propanediol
CAS504-63-2
Humectant / solubilizer
25.495%
Glycerin
CAS56-81-5
Humectant carrier
10.198%
Epilobium Angustifolium Flower/Leaf/Stem Extract
CASContact for COA
Starting botanical load 4% · modeled extracted solids, not an assay
Active botanical extract (triterpene-rich)
1.12%
Linatural™ MBS-4
Multifunctional preservative
2%
Inside Linatural™ MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (this stock)
1.0% – 5.0%
pH compatibility
4.5 – 5.1 (stock target; finished-formula pH window per stability data)
Solubility
Highly water-soluble; fully miscible in hydroglycerin systems.
Temperature
Heat-sensitive, incorporate below 40°C during cool-down phase.
Incompatibilities
As a high-tannin botanical, may precipitate or destabilize with certain excipients. Pre-formulation compatibility testing is recommended.
Pairs well with
Water, Propanediol, Glycerin (common hydroglycerin systems)
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs
Need something different?
Custom extract loading, alternate carriers, bulk sizing, or a regulatory packet - reach out and we’ll quote.

Documentation

SDS + TDS are issued per selected recipe. Links swap when you change selections above. A sample COA shows the standard extract QC panel (pH, organoleptic, TAMC/TYMC). Lot-specific COAs ship with every order.

Phytochemistry note

We cook the raw botanical powder into the selected carrier. The botanical carries polar phenolics, flavonoid glycosides, and related extractable fractions. Those markers support antioxidant and skin-conditioning cosmetic stories. This is not a solvent isolate or a standardized marker extract. Lot identity appears on the COA and TDS.

Quality & claims

Quality, process, and what we will (and will not) claim.

This is a ready-to-use cosmetic extract stock, not a finished consumer product and not a standardized marker isolate. We cook the raw botanical powder into the selected hydroglycerin or oil carrier. Aqueous lots are released on pH, organoleptic, TAMC, and TYMC (total counts only). Oil macerates are released on organoleptic only. A sample COA is on this page; the lot-specific COA ships with the order.

Download sample Certificate of Analysis
What we sell
A made-to-order cosmetic extract stock in 1 kg, 5 kg, and 17 kg. Choose aqueous hydroglycerin (base + preservation) or, where offered, an oil macerate. Strength is Standard or Concentrated. We sell the INCI extract in our carrier - not a supplier trade-name SKU and not a finished leave-on product.
How it is made
We cook the raw botanical powder into the selected hydroglycerin or oil carrier on our robotic platform, then fill to order. Aqueous stocks ship preserved at the system you select. Oil macerates ship anhydrous (no water-phase preservative). Extracted solids on the composition bar are modeled from the starting botanical load - they are not an HPLC assay.
Standard extract QC
  • Organoleptic (all stocks): appearance, odor, consistency
  • Aqueous only: pH (typical 4.5–5.5 for the selected preservative)
  • Aqueous only: TAMC < 100 CFU/g and TYMC < 10 CFU/g (total counts; no pathogen panel)
  • Oil macerates: organoleptic only - no pH, TAMC, or TYMC
Not on the default panel: marker assays, heavy metals, pesticides, residual solvents, or individual pathogen screens. Ask if you need those quoted.
What we can claim
Cosmetic structure/function language only: skin- or hair-conditioning, antioxidant cosmetic stories, and appearance-based well-aging positioning supported by published literature. INCI, composition, SDS/TDS, and a lot COA. Compatible with intended cosmetic use under FDA cosmetic rules and EU 1223/2009 when the finished formula is properly assessed.
What we cannot claim
No disease, treatment, cure, or prevent claims. No ingestible / TCM drug positioning. No guarantee that published pathways will reproduce in your finished formula. Not certified organic, COSMOS, vegan, kosher, halal, or non-GMO unless a separate certificate is issued. We do not sell this as a dietary supplement. We do not name a vendor or country of origin for the incoming powder on this page.
Documents with the order
SDS and TDS for the selected recipe (links above swap with your selection). Sample COA on this page for the standard QC panel. Lot-specific COA ships with every batch. Custom loading, alternate carriers, or a fuller regulatory packet - email materials@formulatelabs.ai.
What exactly ships?
A bulk cosmetic extract stock in 1 kg, 5 kg, or 17 kg. Aqueous lots use Water + Propanediol + Glycerin or classic hydroglycerin, with a selectable preservation system. Oil macerates (where offered) ship in a carrier oil, unpreserved. Botanical INCI is Epilobium Angustifolium Flower/Leaf/Stem Extract. The finished-product INCI is the full selected deck in descending order. We sell the INCI extract in our carrier, not a supplier trade-name SKU.
How is it made?
We start from the raw botanical powder and cook it into the selected hydroglycerin or oil carrier on our robotic platform, then fill to order. Aqueous stocks ship preserved at the system you select. Oil macerates ship anhydrous (no water-phase preservative). Extracted solids on the composition bar are modeled from the starting botanical load - they are not an HPLC marker assay.
What is on the COA?
Aqueous: appearance, odor, consistency, pH, TAMC < 100 CFU/g, TYMC < 10 CFU/g (total counts only - no pathogen panel). Oil: organoleptic only; no pH, TAMC, or TYMC. The sample COA on this page shows representative passing numbers. Your lot COA carries the real lot number and measurements. Marker assays, heavy metals, pesticides, residual solvents, and individual pathogen screens are not on the default panel. Ask if you need those quoted.
Is this a standardized marker isolate?
No. This is a whole-botanical powder extraction into the selected carrier, not a solvent isolate and not a standardized marker extract unless a separate assay is specified and quoted. Composition percentages for extracted solids are modeled from starting botanical load.
Where is the botanical from, and is the stock certified?
Stock is manufactured to order in Fenton, MO. Incoming botanical powder varies by lot. We do not list a vendor or country of origin on this page. The finished extract stock is not certified organic, COSMOS, vegan, kosher, halal, or non-GMO unless a separate certificate is issued. No fragrance is added. Full deck disclosure is on the SDS for the selected recipe.
What can we claim on a finished formula?
Cosmetic structure/function language only: skin- or hair-conditioning, antioxidant cosmetic stories, and appearance-based well-aging positioning. Published literature is due diligence, not finished-product claim substantiation. Do not claim diagnosis, treatment, cure, or prevention of disease. Do not position this as an ingestible, TCM drug, or dietary supplement.
Lead time and shelf life?
Made to order on our robotic platform. Aqueous target shelf life is 12–18 months at room temperature, 18–24 months refrigerated, preservative-dependent. Oil macerates are similar unopened ranges; protect from light and heat. Use-by on the lot COA governs the batch you receive.
Compliance & safety

The fine print, in plain English.

What it’s for
Cosmetic products, generally accepted in key markets including North America and Europe.
Claims guidance
Formulations may claim soothing, calming, redness reduction, sebum regulation, blemish control, skin conditioning, antioxidant protection, and support for a balanced scalp environment.
Storage
  • Store tightly closed, protected from light and heat.
  • Refrigeration optional for extended shelf life per TDS.
  • Aqueous botanical - monitor for color shift over time.
Regulatory
  • Finished-product INCI lists components in descending order per the selected variant deck.
  • Cosmetic function: skin conditioning agent, antioxidant, sebum regulating agent, soothing agent
  • Full blend composition disclosed on SDS/TDS (FL-EAE series).
  • Formulators should always verify compliance with local regulations for their specific application.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for intended cosmetic use when properly incorporated.
Handling
Store in opaque, UV-protected packaging to prevent photodegradation. Incorporate into formulations during the cool-down phase, at temperatures below 40°C.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

1 kg
$150.00
Added to cart View cart →