Something Exciting is Coming

We're working hard to bring you an amazing new experience. Stay tuned for updates!

Launching 2026
Schedule a Call
Botanical Extract · Aqueous Hydroglycerin · 5% Loading

Canadian Willowherb Extract

Epilobium Angustifolium Flower/Leaf/Stem Extract · 5% aqueous hydroglycerin stock

Discover the soothing and balancing power of Epilobium Angustifolium. Our standardized extract, featuring key actives like Oenothein B, flavonoids, and phenolic acids, is supplied as a fixed 5% hydroglycerin stock, distinguishing it from general Canadian Willowherb or Fireweed raw materials.

  • Fixed 5% Epilobium Angustifolium Flower/Leaf/Stem Extract in Water + Propanediol + Glycerin Extract or Hydroglycerin Extract base
  • Four preservation systems - 8 recipes total, all made-to-order
  • COA + SDS + TDS per base/preservative variant · 500 g to 17 kg
Base: Water + Propanediol + Glycerin Extract Full composition
Preservation: Linatural MBS-4 INCI breakdown
Aqueous stock with water, propanediol, and glycerin carrying 5% botanical extract. Balanced humectancy with propanediol solubilization - default for oily, blemish-prone, and sensitive skin serums and toners. Preserved with Linatural MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this stock, ordered by %)
Water, Propanediol, Glycerin, Epilobium Angustifolium Flower/Leaf/Stem Extract, Propanediol, Ethylhexylglycerin, Benzoic Acid
Size: 500 g Formulation guide
1
Oenothein B
Key macrocyclic ellagitannin
COA & SDS
Every batch
Cosmetic grade
Aqueous hydroglycerin
Specifications

Everything you need on the technical data sheet.

INCI Name
Epilobium Angustifolium Flower/Leaf/Stem Extract
Common names
Canadian Willowherb · Fireweed · Willowherb
Loading
5% extract in hydroglycerin stock
Solubility
Aqueous / water phase
Appearance
Amber to brown aqueous fluid
pH (bulk material)
4.5 – 5.1
Add at
Cool-down < 40–45 °C
Shelf Life
12–18 mo RT · 18–24 mo refrigerated
epilobium botanical extract - epilobium hydroglycerin stock Canadian Willowherb · Fireweed
The extract

The Multi-Functional Science of Canadian Willowherb

Botanical Identity: Derived from the resilient *Epilobium Angustifolium* plant, also commonly known as Canadian Willowherb, Fireweed, or simply Willowherb. Our Product: We provide the pure botanical extract, identified by its INCI name Epilobium Angustifolium Flower/Leaf/Stem Extract, distinct from various supplier-specific trade names or branded ingredients.

Dual mechanism: The cosmetic activity of Epilobium Angustifolium Flower/Leaf/Stem Extract is multi-faceted, driven by its rich polyphenol profile, primarily the macrocyclic ellagitannin Oenothein B. It acts as a potent inhibitor of 5-α-reductase, helping to balance surface oils, and suppresses inflammatory pathways by inhibiting lipoxygenase and cyclooxygenases (COX-1 and COX-2) to reduce visible erythema and irritation. Furthermore, it supports the skin's structural matrix by inhibiting matrix metalloproteinases (MMPs) like collagenase, elastase, and hyaluronidase, contributing to the appearance of skin firmness and texture. Additional benefits include direct antioxidant activity against reactive oxygen species (ROS) and antibacterial properties against microbes relevant to blemishes, such as *P. acnes*.

Use levels: For optimal efficacy, particularly for rapid anti-erythema effects, Formulate Labs' standardized hydroglycerin stock is typically incorporated into formulations at a rate of 1.0% to 5.0%. Optimal results are often observed between 1.0% and 3.0%.

Market context: Epilobium Angustifolium Flower/Leaf/Stem Extract is a versatile active competing in the high-performance botanical space. Products in this category are often positioned for rapid anti-irritant effects, with claims around reducing visible redness from chemical or UV exposure. Others emphasize lipid-soluble properties for biomimetic skin barrier support and protection from oxidative stress, while some are aggressively marketed for managing hyperseborrhoea and blemishes through potent anti-androgenic and antimicrobial activity.

Pricing context: B2B pricing for standardized, cosmetic-grade liquid Epilobium Angustifolium extracts is premium due to specialized extraction and quality control. While raw botanical powders are less expensive, they are unsuitable for direct cosmetic formulation. Formulate Labs offers its standardized hydroglycerin extract at competitive rates, such as $143.00 for a 500 g sample, $220.00 for 1 kg, and $3,179.00 for a 17 kg pail.

We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*

Epilobium Angustifolium Flower/Leaf/Stem Extract delivers multi-faceted cosmetic activity, primarily driven by its rich profile of polyphenols, including the macrocyclic ellagitannin Oenothein B, alongside supportive flavonoids and phenolic acids. This potent peptide addresses key concerns related to skin irritation, blemishes, and overall structural integrity. It functions as a powerful inhibitor of 5-α-reductase, an enzyme critically linked to sebum production, thereby helping to balance surface oils on both skin and scalp. For soothing applications, it actively suppresses inflammatory pathways by inhibiting lipoxygenase and cyclooxygenases (COX-1 and COX-2), leading to a visible reduction in erythema and sensations of irritation. Furthermore, its ability to inhibit matrix metalloproteinases (MMPs) such as collagenase, elastase, and hyaluronidase helps preserve the appearance of skin firmness and texture, supporting the skin’s structural matrix. These actions are complemented by direct antioxidant activity through the neutralization of reactive oxygen species (ROS) and antibacterial properties against microbes like P. acnes, making it exceptionally well-suited for formulations targeting oily, blemish-prone, and sensitive skin.

Market context: Epilobium Angustifolium Flower/Leaf/Stem Extract is a highly competitive, multi-functional active that stands alongside other high-performance botanicals in the market. Actives found in Canadian Willowherb™-class products are often recognized for their rapid anti-irritant effects, specifically reducing visible redness from chemical or UV exposure. The extract found in EPILOBIUM Oléoactif®-class actives, differentiated by a patented oil-based extraction, emphasizes lipid-soluble benefits for barrier reinforcement and moisturization. Meanwhile, the extract found in Seborilys-class actives typically appears in synergistic botanical blends, marketed for aggressive management of hyperseborrhoea and blemishes through potent anti-androgenic and antimicrobial activity. Formulate Labs offers Epilobium Angustifolium Flower/Leaf/Stem Extract as a versatile and standardized raw material, distinct from these branded end-products.

Formulate Labs provides Epilobium Angustifolium Flower/Leaf/Stem Extract in a cosmetic-grade hydroglycerin base, meticulously standardized for its Oenothein B content. This ensures a consistent, high-performance active ingredient, ready for seamless integration into your formulations. Our robust supply chain and quality control guarantee the purity and efficacy required for professional cosmetic development.

We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*

5%
Fixed extract loading
2
Hydroglycerin bases
4
Preservation options
Aqueous
Water-phase compatible
Ingredient deck assessment

What this material is and isn’t.

Botanical
Leaf/stem extract; pentacyclic triterpene saponins
Aqueous stock
Hydroglycerin carrier; water phase
Cruelty-free
No animal testing in our process
Cosmetic grade
For professional formulation use

Our product is identified by its INCI name, Epilobium Angustifolium Flower/Leaf/Stem Extract, distinct from various supplier-specific trade names (Canadian Willowherb, Fireweed, Willowherb).

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Soothing & Calming*
Helps to visibly reduce erythema and sensations of irritation by suppressing inflammatory pathways, ideal for sensitive skin.
Blemish & Oil Control
Inhibits 5-α-reductase to balance surface oils and provides antibacterial action against *P. acnes* for clearer-looking skin.
Supports Skin Structure*
Inhibits key matrix metalloproteinases (MMPs) like collagenase and elastase, helping to preserve the appearance of skin firmness and texture.
Antioxidant Protection
Neutralizes reactive oxygen species (ROS), providing direct antioxidant benefits to help protect the skin from environmental stressors.

This product refers to the raw material Epilobium Angustifolium Flower/Leaf/Stem Extract and not to any branded or finished cosmetic products containing this extract.

Published research

Peer-reviewed literature for due diligence.

The efficacy of Epilobium Angustifolium Flower/Leaf/Stem Extract is robustly supported by peer-reviewed scientific literature. Research highlights its diverse activities, including potent antioxidant capacity, anti-inflammatory properties, sebum-regulating effects, and antimicrobial action, validating its multi-functional benefits for cosmetic applications. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

2022
Review
Molecules

Therapeutic Potential of Polyphenols from *Epilobium angustifolium* (Fireweed)

Schepetkin IA, et al.

This review emphasizes the dermocosmetic value of Oenothein B, the extract's primary bioactive, in neutralizing damaging reactive oxygen species and inhibiting COX-1/COX-2 pathways, supporting its role in soothing irritated skin.

2016
Research
Phytotherapy Research

Chemical composition, antioxidative and anti-inflammatory activity of extracts prepared from aerial parts of *Epilobium* species

Granica S, et al.

This study confirms the antibacterial action of the extract's polyphenols and ellagitannins against *P. acnes*, a key factor in blemish-prone skin, and demonstrates potent immunomodulatory activity suitable for calming and rebalancing skin.

2024
Research
Cosmetics

*Epilobium angustifolium* L. Extract as a Multifunctional and Sustainable Active Ingredient for Skin Care Applications

Kurek-Górecka A, et al.

Pharmacological studies validate the extract's effectiveness as a sustainable cosmetic ingredient for managing surface oil and soothing skin, making it an excellent choice for products targeting blemishes, dandruff, and acute redness.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this hydroglycerin stock.

Bulk composition at fixed 5% Epilobium Angustifolium Flower/Leaf/Stem Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-EAE-W1-MBS4-5PCT-001).

Water · 58.737% Propanediol · 24.474% Glycerin · 9.789% Epilobium Angustifolium Flower/Leaf/Stem Extract · 5% Linatural™ MBS-4 · 2%
Water
CAS7732-18-5
Solvent
58.737%
Propanediol
CAS504-63-2
Humectant / solubilizer
24.474%
Glycerin
CAS56-81-5
Humectant carrier
9.789%
Epilobium Angustifolium Flower/Leaf/Stem Extract
CASContact for COA
Active botanical extract (triterpene-rich)
5%
Linatural MBS-4
Multifunctional preservative
2%
Inside Linatural MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (this stock)
1.0% – 5.0%
pH compatibility
4.5 – 5.1 (stock target; finished-formula pH window per stability data)
Solubility
Highly water-soluble; fully miscible in hydroglycerin systems.
Temperature
Heat-sensitive, incorporate below 40°C during cool-down phase.
Incompatibilities
As a high-tannin botanical, may precipitate or destabilize with certain excipients. Pre-formulation compatibility testing is recommended.
Pairs well with
Water, Propanediol, Glycerin (common hydroglycerin systems)
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs

Documentation

SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.

Need something different?
Custom extract loading, alternate carriers, bulk sizing, or a regulatory packet - reach out and we’ll quote.
Compliance & safety

The fine print, in plain English.

What it’s for
Cosmetic products, generally accepted in key markets including North America and Europe.
Claims guidance
Formulations may claim soothing, calming, redness reduction, sebum regulation, blemish control, skin conditioning, antioxidant protection, and support for a balanced scalp environment.
Storage
  • Store tightly closed, protected from light and heat.
  • Refrigeration optional for extended shelf life per TDS.
  • Aqueous botanical - monitor for color shift over time.
Regulatory
  • Finished-product INCI lists components in descending order per the selected variant deck.
  • Cosmetic function: skin conditioning agent, antioxidant, sebum regulating agent, soothing agent
  • Full blend composition disclosed on SDS/TDS (FL-EAE series).
  • Formulators should always verify compliance with local regulations for their specific application.
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for intended cosmetic use when properly incorporated.
Handling
Store in opaque, UV-protected packaging to prevent photodegradation. Incorporate into formulations during the cool-down phase, at temperatures below 40°C.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

500 g
$143.00
Added to cart View cart →