Recombinant sh-Oligopeptide-1 (EGF)
Recombinant human EGF (sh-Oligopeptide-1) in a stabilizing aqueous suspension for cosmetic renewal serums.*
Suspension stabilizers in the shipped bulk are processing aids and are not declared on the finished-product INCI when the material is used as directed. See SDS for details.
sh-Oligopeptide-1 · CAS 62253-63-8 · ~6,045 Da
sh-Oligopeptide-1 is a 53-amino acid recombinant peptide designed as a biomimetic analog to human Epidermal Growth Factor (EGF). By binding to the epidermal growth factor receptor (EGFR) on keratinocytes and fibroblasts, it activates key signal transduction pathways, initiating a cellular cascade that stimulates proliferation, accelerates epidermal renewal, and upregulates the synthesis of extracellular matrix components like collagen, elastin, and hyaluronic acid. Within cosmetic science, this peptide is positioned as a high-performance bioactive for premium anti-aging formulations, post-procedure recovery matrices, and targeted scar-reduction serums.
Market context: — While Formulate Labs provides sh-Oligopeptide-1 under its INCI designation, not specific trade-name SKUs, understanding the competitive landscape highlights various approaches to this potent peptide. Competitors market sh-Oligopeptide-1, for example, as plant-derived biomimetic structural boosters (found in Epitensive™-class actives), bacterially fermented peptides optimized for room-temperature stability (found in SpecBio™ EGF Plus-class actives), or nano-encapsulated for enhanced penetration (found in CG-EGF-class actives). Formulate Labs focuses on delivering a rigorously validated, high-purity sh-Oligopeptide-1 raw material for your bespoke cosmetic developments.
Formulate Labs provides sh-Oligopeptide-1 in a targeted stabilizing aqueous suspension, meticulously crafted to ensure optimal stability and bioavailability. Our concentrate simplifies integration into cosmetic formulations, allowing chemists to achieve final product concentrations typically ranging from 1 to 10 ppm for potent, efficacious results.
We ship recombinant EGF in a stabilizing aqueous suspension at two strengths — standard (0.08%) for typical cosmetic dilution workflows, or a 10X lab concentrate (0.8%) when you want maximum loading in minimal volume. The suspension helps protect the active during refrigerated storage and reduce deterioration — see SDS for composition details.*
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications. If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs supplies sh-Oligopeptide-1 under its INCI designation for cosmetic raw material use and does not sell branded or trade-name finished products.
Epidermal Growth Factor (sh-Oligopeptide-1) is widely cited in skin-science literature for keratinocyte renewal, EGFR signaling, and cosmetic recovery positioning. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
A three-month study demonstrating that daily topical application of barley-bioengineered EGF serum significantly improves fine lines, pore size, and skin texture.
Combining recombinant EGF with crosslinked hyaluronic acid yields statistically significant enhancements in skin smoothness, firmness, and barrier function.
Systematic review stressing that while cosmetic-grade sh-oligopeptide-1 is widely used for anti-aging, rigorous preclinical bioactivity validation remains necessary.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the bulk composition as it ships. Updates dynamically when you change the strength above. The active line shows the EGF loading at the selected concentration. Suspension stabilizers in the shipped bulk protect the active during storage and are not declared on the finished-product cosmetic INCI when the protein is reconstituted / diluted into your formula as directed. Full stabilizer identity and concentration are on the SDS.
SDS + TDS are issued per strength. Links swap when you change concentration above. COA is batch-specific and ships with the order.
Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.
