Dipeptide Diaminobutyroyl Benzylamide Diacetate cosmetic peptide suspension · peptide found in SYN-AKE-class actives™ / Waglerin-1-mimetic neuromodulator · choose base, strength, and preservation
Dipeptide Diaminobutyroyl Benzylamide Diacetate, a peptide found in SYN-AKE-class actives, offers a biomimetic approach to visibly smooth dynamic expression lines by targeting neuromuscular activity; Formulate Labs supplies Dipeptide Diaminobutyroyl Benzylamide Diacetate only – we do not sell or represent SYN-AKE.
Waglerin-1 mimic (SYN-AKE diacetate) · CAS 82394-93-4
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic biomimetic tripeptide engineered to replicate the localized neuromuscular blocking effects of Waglerin-1, a neurotoxin found in temple viper venom. Positioned as a topical, non-invasive alternative to injectable neuromodulators, it functions as a reversible antagonist at the muscular nicotinic acetylcholine receptor (mnAChR). By temporarily blocking acetylcholine binding at the postsynaptic membrane, this peptide prevents sodium ion uptake, thereby keeping facial muscles relaxed and visibly smoothing dynamic expression lines without causing systemic paralysis or loss of facial mobility. Its primary application category is cosmetic leave-on skin care.
Market context: Competitive marketing for actives like Dipeptide Diaminobutyroyl Benzylamide Diacetate often leverages the “snake venom” biomimicry narrative, positioning them as fast-acting, topical alternatives to injectables for expression lines. Formulate Labs strictly supplies the INCI active, Dipeptide Diaminobutyroyl Benzylamide Diacetate, and does not sell supplier-branded SKUs such as SYN-AKE. Competitor campaigns frequently target both mature and millennial demographics, emphasizing an 'age-freezing' effect that helps prevent mimic wrinkles from setting into permanent static lines. Commercial positioning also highlights the synthetic peptide's safety, vegan-friendly origins, and fully reversible muscle relaxation, distinctly separating its efficacy from the actual toxicity of snake venom.
Formulate Labs offers Dipeptide Diaminobutyroyl Benzylamide Diacetate as a 0.1% standard or 1% lab concentrate, expertly suspended in either a Glycerin/Water base or our highly compatible Sea Kelp Bioferment. These suspensions are available in convenient 100 g, 1 kg, and 18 kg pack sizes, providing flexibility for various production scales. The peptide exhibits excellent water and glycol solubility, making it easy to integrate into a wide range of cosmetic formulations.
Hair-care note: like all neuromodulating peptides, SYN-AKE has no practical hair application — follicles do not rely on muscular contraction for anagen, proliferation, or anchoring, so scalp serums and follicle treatments gain zero physiological benefit.*
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Trade names such as SYN-AKE refer to supplier-branded actives; Formulate Labs supplies Dipeptide Diaminobutyroyl Benzylamide Diacetate only — we do not sell or represent SYN-AKE.
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a well-researched peptide, particularly for its biomimetic properties inspired by neurotoxins found in snake venom. While often compared to actives found in SYN-AKE-class products, Formulate Labs supplies Dipeptide Diaminobutyroyl Benzylamide Diacetate only and does not represent or sell SYN-AKE. The following studies highlight its mechanism of action and efficacy in cosmetic applications. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Clinical and ex vivo studies demonstrated that serums containing this dipeptide significantly improve static and dynamic wrinkles while upregulating elastic and collagen fibers.
A four-week in vivo study confirmed a 13.52% reduction in visible mimic wrinkle area when using a 4% topical formulation containing this dipeptide.
Formulations mimicking Waglerin-1 act as targeted nicotinic acetylcholine receptor antagonists for expression-line improvement.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the DD-DBD loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
