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ReviewSee PubMed record
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Peer-reviewed reference cited in Deep Research evidence brief.
Coptis Chinensis Root Extract
Formulate Labs offers a standard or concentrated hydroglycerin stock of Coptis Chinensis Root Extract, characterized by key actives such as Berberine, palmatine, coptisine, and epiberberine. Distinct from common trade names like Coptis, Huang Lian, or Goldthread, our INCI-specific material provides robust benefits for cosmetic applications focusing on skin clarity and comfort.
Coptis Chinensis Root
Botanical Identity: Coptis Chinensis Root Extract (INCI: Coptis Chinensis Root Extract) is derived from the root of the Coptis chinensis plant. Trade Names: It is also known by common names such as Coptis, Huang Lian, and Goldthread. Formulate Labs provides this ingredient under its INCI name, ensuring clear identification separate from various supplier SKUs or trade-specific appellations.
Dual mechanism: Coptis Chinensis Root Extract provides multifunctional benefits for skin health and appearance, driven by its rich alkaloid content. The primary active, Berberine, exhibits broad-spectrum antimicrobial activity, helping to balance the microflora by addressing organisms such as *C. acnes* and *Malassezia*. From a cosmetic science perspective, the extract helps to soothe compromised skin by downregulating key pro-inflammatory cytokine pathways (NF-κB and MAPK), which reduces the appearance of redness and irritation. Furthermore, it supports the integrity of the skin's natural defenses by helping to restore filaggrin, a key protein essential for a robust and healthy skin barrier.
Use levels: Formulate Labs recommends a typical use level of 0.2% to 3.0% of this standard or concentrated hydroglycerin stock, depending on the desired performance in the final cosmetic formulation.
Market context: This material is positioned for its scientifically validated botanical active properties suitable for clinical clean beauty applications, especially for skin prone to blemishes, sensitivity, and barrier dysfunction, offering an alternative to conventional synthetic ingredients. It is marketed for its dual-action performance, combining antimicrobial properties for clarifying blemish-prone skin with potent soothing benefits for calming sensitive and reactive skin types. Its inherent yellow tint can also be leveraged in the growing "makeup care" or "skincare-hybrid" trend as a natural colorant in primers or concealers while delivering sebum-regulating and antioxidant benefits.
We ship standard or concentrated extract stock with selectable preservation - ready to meter into finished formulas at the use rates in the formulation guide below.*
Formulate Labs refers to ingredients by their INCI name to ensure clarity, differentiating them from common trade or context names (Coptis, Huang Lian, Goldthread).
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.
Coptis Chinensis Root Extract is documented in cosmetic peptide/protein literature. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Peer-reviewed reference cited in Deep Research evidence brief.
Peer-reviewed reference cited in Deep Research evidence brief.
Peer-reviewed reference cited in Deep Research evidence brief.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the extract stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
Bulk composition at the selected Coptis Chinensis Root Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at the selected loading. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-CCR-W1-MBS4-5PCT-001).
SDS + TDS are issued per selected recipe. Links swap when you change selections above. A sample COA shows the standard extract QC panel (pH, organoleptic, TAMC/TYMC). Lot-specific COAs ship with every order.
We cook the raw botanical powder into the selected carrier. The botanical carries polar phenolics, flavonoid glycosides, and related extractable fractions. Those markers support antioxidant and skin-conditioning cosmetic stories. This is not a solvent isolate or a standardized marker extract. Lot identity appears on the COA and TDS.
This is a ready-to-use cosmetic extract stock, not a finished consumer product and not a standardized marker isolate. We cook the raw botanical powder into the selected hydroglycerin or oil carrier. Aqueous lots are released on pH, organoleptic, TAMC, and TYMC (total counts only). Oil macerates are released on organoleptic only. A sample COA is on this page; the lot-specific COA ships with the order.
Download sample Certificate of AnalysisStatements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.