See linked PubMed record
Peer-reviewed reference cited in Deep Research evidence brief.
Coptis Chinensis Root Extract · 5% aqueous hydroglycerin stock
Formulate Labs offers a fixed 5% hydroglycerin stock of Coptis Chinensis Root Extract, characterized by key actives such as Berberine, palmatine, coptisine, and epiberberine. Distinct from common trade names like Coptis, Huang Lian, or Goldthread, our INCI-specific material provides robust benefits for cosmetic applications focusing on skin clarity and comfort.
Coptis Chinensis Root
Botanical Identity: Coptis Chinensis Root Extract (INCI: Coptis Chinensis Root Extract) is derived from the root of the Coptis chinensis plant. Trade Names: It is also known by common names such as Coptis, Huang Lian, and Goldthread. Formulate Labs provides this ingredient under its INCI name, ensuring clear identification separate from various supplier SKUs or trade-specific appellations.
Dual mechanism: Coptis Chinensis Root Extract provides multifunctional benefits for skin health and appearance, driven by its rich alkaloid content. The primary active, Berberine, exhibits broad-spectrum antimicrobial activity, helping to balance the microflora by addressing organisms such as *C. acnes* and *Malassezia*. From a cosmetic science perspective, the extract helps to soothe compromised skin by downregulating key pro-inflammatory cytokine pathways (NF-κB and MAPK), which reduces the appearance of redness and irritation. Furthermore, it supports the integrity of the skin's natural defenses by helping to restore filaggrin, a key protein essential for a robust and healthy skin barrier.
Use levels: Formulate Labs recommends a typical use level of 0.2% to 3.0% of this fixed 5% hydroglycerin stock, depending on the desired performance in the final cosmetic formulation.
Market context: This material is positioned for its scientifically validated botanical active properties suitable for clinical clean beauty applications, especially for skin prone to blemishes, sensitivity, and barrier dysfunction, offering an alternative to conventional synthetic ingredients. It is marketed for its dual-action performance, combining antimicrobial properties for clarifying blemish-prone skin with potent soothing benefits for calming sensitive and reactive skin types. Its inherent yellow tint can also be leveraged in the growing "makeup care" or "skincare-hybrid" trend as a natural colorant in primers or concealers while delivering sebum-regulating and antioxidant benefits.
Pricing context: While specific B2B wholesale pricing for cosmetic-grade hydroglycerin extracts of Coptis Chinensis is sparse, market data for related bulk raw powders and standardized berberine extracts shows a wide range from $8.00/kg to $150.78/kg, varying significantly based on alkaloid purity and processing. Based on this, a realistic price ladder for Formulate Labs' hydroglycerin extract is $123.50 for a 500g sample, $190.00 per kg, and $161.50 per kg for a 17kg drum.
We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*
Formulate Labs refers to ingredients by their INCI name to ensure clarity, differentiating them from common trade or context names (Coptis, Huang Lian, Goldthread).
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.
Coptis Chinensis Root Extract is documented in cosmetic peptide/protein literature. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Peer-reviewed reference cited in Deep Research evidence brief.
Peer-reviewed reference cited in Deep Research evidence brief.
Peer-reviewed reference cited in Deep Research evidence brief.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
Bulk composition at fixed 5% Coptis Chinensis Root Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-CCR-W1-MBS4-5PCT-001).
SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.
Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.