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Botanical Extract · Aqueous Hydroglycerin · 5% Loading

Coptis Root Extract

Coptis Chinensis Root Extract · 5% aqueous hydroglycerin stock

Formulate Labs offers a fixed 5% hydroglycerin stock of Coptis Chinensis Root Extract, characterized by key actives such as Berberine, palmatine, coptisine, and epiberberine. Distinct from common trade names like Coptis, Huang Lian, or Goldthread, our INCI-specific material provides robust benefits for cosmetic applications focusing on skin clarity and comfort.

  • Fixed 5% Coptis Chinensis Root Extract in Water + Propanediol + Glycerin Extract or Hydroglycerin Extract base
  • Four preservation systems - 8 recipes total, all made-to-order
  • COA + SDS + TDS per base/preservative variant · 500 g to 17 kg
Base: Water + Propanediol + Glycerin Extract Full composition
Preservation: Linatural MBS-4 INCI breakdown
Aqueous stock with water, propanediol, and glycerin carrying 5% botanical extract. Balanced humectancy with propanediol solubilization - default for blemish-prone and sensitive skin serums and toners. Preserved with Linatural MBS-4 at 2%.
Target pH
4.5 – 5.1
Shelf life (RT · cold)
12–18 mo · 18–24 mo
Final INCI deck (this stock, ordered by %)
Water, Propanediol, Glycerin, Coptis Chinensis Root Extract, Propanediol, Ethylhexylglycerin, Benzoic Acid
Size: 500 g Formulation guide
1
Coptis Root
Alkaloid-rich extract
COA & SDS
Every batch
Cosmetic grade
Aqueous hydroglycerin
Specifications

Everything you need on the technical data sheet.

INCI Name
Coptis Chinensis Root Extract
Common names
Coptis · Huang Lian · Goldthread
Loading
5% extract in hydroglycerin stock
Solubility
Aqueous / water phase
Appearance
Amber to brown aqueous fluid
pH (bulk material)
4.5 – 5.1
Add at
Cool-down < 40–45 °C
Shelf Life
12–18 mo RT · 18–24 mo refrigerated
coptis botanical extract - coptis hydroglycerin stock Coptis Chinensis Root
The extract

The Story of Coptis Chinensis Root Extract

Botanical Identity: Coptis Chinensis Root Extract (INCI: Coptis Chinensis Root Extract) is derived from the root of the Coptis chinensis plant. Trade Names: It is also known by common names such as Coptis, Huang Lian, and Goldthread. Formulate Labs provides this ingredient under its INCI name, ensuring clear identification separate from various supplier SKUs or trade-specific appellations.

Dual mechanism: Coptis Chinensis Root Extract provides multifunctional benefits for skin health and appearance, driven by its rich alkaloid content. The primary active, Berberine, exhibits broad-spectrum antimicrobial activity, helping to balance the microflora by addressing organisms such as *C. acnes* and *Malassezia*. From a cosmetic science perspective, the extract helps to soothe compromised skin by downregulating key pro-inflammatory cytokine pathways (NF-κB and MAPK), which reduces the appearance of redness and irritation. Furthermore, it supports the integrity of the skin's natural defenses by helping to restore filaggrin, a key protein essential for a robust and healthy skin barrier.

Use levels: Formulate Labs recommends a typical use level of 0.2% to 3.0% of this fixed 5% hydroglycerin stock, depending on the desired performance in the final cosmetic formulation.

Market context: This material is positioned for its scientifically validated botanical active properties suitable for clinical clean beauty applications, especially for skin prone to blemishes, sensitivity, and barrier dysfunction, offering an alternative to conventional synthetic ingredients. It is marketed for its dual-action performance, combining antimicrobial properties for clarifying blemish-prone skin with potent soothing benefits for calming sensitive and reactive skin types. Its inherent yellow tint can also be leveraged in the growing "makeup care" or "skincare-hybrid" trend as a natural colorant in primers or concealers while delivering sebum-regulating and antioxidant benefits.

Pricing context: While specific B2B wholesale pricing for cosmetic-grade hydroglycerin extracts of Coptis Chinensis is sparse, market data for related bulk raw powders and standardized berberine extracts shows a wide range from $8.00/kg to $150.78/kg, varying significantly based on alkaloid purity and processing. Based on this, a realistic price ladder for Formulate Labs' hydroglycerin extract is $123.50 for a 500g sample, $190.00 per kg, and $161.50 per kg for a 17kg drum.

We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*

5%
Fixed extract loading
2
Hydroglycerin bases
4
Preservation options
Aqueous
Water-phase compatible
Ingredient deck assessment

What this material is and isn’t.

Botanical
Leaf/stem extract; pentacyclic triterpene saponins
Aqueous stock
Hydroglycerin carrier; water phase
Cruelty-free
No animal testing in our process
Cosmetic grade
For professional formulation use

Formulate Labs refers to ingredients by their INCI name to ensure clarity, differentiating them from common trade or context names (Coptis, Huang Lian, Goldthread).

Made to Order

Built fresh on our robotic platform.

Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.

01
Order placed
You pick a size and quantity. We confirm specs against your formulation if you have one.
02
Robotic production
Your inputs go in. We process, blend, and fill sealed packaging - all inside our AI-powered robotic factory.
03
Batch QC + COA
Every batch is tested for actives, pH, micro, and appearance. A batch-specific COA, SDS, and TDS ship with the order.
Why formulators reach for it

Science-backed cosmetic positioning.

Clarifying & Balancing*
Helps balance skin microflora and address organisms like *C. acnes*, promoting a clearer complexion.
Soothing & Calming*
Downregulates pro-inflammatory pathways to reduce the appearance of redness and irritation in sensitive skin.
Barrier Support*
Supports the integrity of the skin's natural defenses by helping to restore essential barrier proteins like filaggrin.
Scalp Comfort
Addresses *Malassezia* to support a balanced and comfortable scalp environment in clarifying scalp care formulations.

* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.

Published research

Peer-reviewed literature for due diligence.

Coptis Chinensis Root Extract is documented in cosmetic peptide/protein literature. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.

Review
See PubMed record

See linked PubMed record

See journal record

Peer-reviewed reference cited in Deep Research evidence brief.

Review
See PubMed record

See linked PubMed record

See journal record

Peer-reviewed reference cited in Deep Research evidence brief.

Review
See PubMed record

See linked PubMed record

See journal record

Peer-reviewed reference cited in Deep Research evidence brief.

These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.

Composition

What’s in this hydroglycerin stock.

Bulk composition at fixed 5% Coptis Chinensis Root Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-CCR-W1-MBS4-5PCT-001).

Water · 58.737% Propanediol · 24.474% Glycerin · 9.789% Coptis Chinensis Root Extract · 5% Linatural™ MBS-4 · 2%
Water
CAS7732-18-5
Solvent
58.737%
Propanediol
CAS504-63-2
Humectant / solubilizer
24.474%
Glycerin
CAS56-81-5
Humectant carrier
9.789%
Coptis Chinensis Root Extract
CASContact for COA
Active botanical extract (triterpene-rich)
5%
Linatural MBS-4
Multifunctional preservative
2%
Inside Linatural MBS-4
Propanediol
CAS504-63-2
1.7%
Ethylhexylglycerin
CAS70445-33-9
0.2%
Benzoic Acid
CAS65-85-0
0.1%
Formulation guide

Built for chemists who sweat the details.

Typical use rate (this stock)
0.2% to 3.0% (of a 5% stock)
pH compatibility
4.5 – 5.1 (stock target; finished-formula pH window per stability data)
Solubility
Highly soluble in water, propanediol, and glycerin. Well-suited for hydro-glycolic and propanediol-based systems.
Temperature
The extract's alkaloids are sensitive to degradation. Protect finished formulas from direct UV exposure and avoid prolonged processing at temperatures above 60℃ during the cool-down phase.
Incompatibilities
Imparts a strong natural yellow-orange color. May form complexes or cause precipitation with high concentrations of strongly anionic thickeners (e.g., Carbomer) or anionic surfactants due to cationic alkaloids.
Pairs well with
Self-preserving
Yes - 2% Linatural MBS-4. Boost preservation per your finished-formula needs

Documentation

SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.

Need something different?
Custom extract loading, alternate carriers, bulk sizing, or a regulatory packet - reach out and we’ll quote.
Compliance & safety

The fine print, in plain English.

What it’s for
This ingredient is a botanical extract from *Coptis chinensis* roots, traditionally recognized for its beneficial properties. It is intended for use as a cosmetic ingredient.
Claims guidance
Formulators are responsible for conducting their own safety and stability testing to ensure compatibility and compliance for their specific application and target market. All claims and uses must comply with regional cosmetic regulations.
Storage
  • Store tightly closed, protected from light and heat.
  • Refrigeration optional for extended shelf life per TDS.
  • Aqueous botanical - monitor for color shift over time.
Regulatory
  • Finished-product INCI lists components in descending order per the selected variant deck.
  • Cosmetic function: skin conditioning agent, soothing agent, antimicrobial, antioxidant
  • Full blend composition disclosed on SDS/TDS (FL-CCR series).
  • Compatible with FDA cosmetic regulations and EU 1223/2009 for intended cosmetic use when properly incorporated.
Handling
Formulators are responsible for conducting their own safety and stability testing to ensure compatibility.
Questions
Documentation, regulatory, or custom sizing - email materials@formulatelabs.ai.

Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.

500 g
$123.50
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