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ReviewSee PubMed record
See linked PubMed record
Peer-reviewed reference cited in Deep Research evidence brief.
Centella Asiatica Leaf/Stem Extract
Pentacyclic triterpene saponins from Centella asiatica at standard or concentrated loading in aqueous hydroglycerin stock. Published work links asiaticoside and madecassoside to TGF-β/Smad collagen support and NF-κB-associated erythema calming - water-phase compatible in our preserved INCI extract, not a supplier-branded cica SKU.*
Centella asiatica · Madecassoside / asiaticoside triterpenes
Centella asiatica is known in herbal tradition as gotu kola and tiger grass, and in modern cosmetics as cica - a supplier marketing shorthand, not an INCI name. Formulate Labs ships Centella Asiatica Leaf/Stem Extract; we do not sell or represent supplier-branded cica SKUs.*
Dual mechanism: Asiaticoside, madecassoside, asiatic acid, and madecassic acid support type I/III collagen and hyaluronic-acid appearance via TGF-β/Smad signaling while modulating NF-κB-associated pathways linked to visible erythema calming - the science behind modern cica serums, creams, and post-treatment leave-ons.*
Use levels: Dose 0.5% to 5.0% of this extract stock in finished formulas (0.025% to 0.25% extract as-is) - 0.5–2.0% for daily moisturizers, 3.0–5.0% for intensive serums.*
Market context: Premium suppliers position green-fractionated centella for anti-aging and microcirculation claims; APAC innovators lead with purified TECA for rapid barrier-support cica therapy. Formulators commonly pair centella with panthenol, ceramides, or hyaluronic acid for multi-functional soothing decks.*
We ship standard or concentrated extract stock with selectable preservation - ready to meter into finished formulas at the use rates in the formulation guide below.*
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications. Trade names (cica, gotu kola, tiger grass) are cited for formulator context only - our product is the INCI extract in our suspension, not a supplier-branded cica active.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.
Centella Asiatica Leaf/Stem Extract is documented in cosmetic peptide/protein literature. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Peer-reviewed reference cited in Deep Research evidence brief.
Peer-reviewed reference cited in Deep Research evidence brief.
Peer-reviewed reference cited in Deep Research evidence brief.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the extract stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
Bulk composition at the selected Centella Asiatica Leaf/Stem Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at the selected loading. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-CAE-W1-MBS4-5PCT-001).
SDS + TDS are issued per selected recipe. Links swap when you change selections above. A sample COA shows the standard extract QC panel (pH, organoleptic, TAMC/TYMC). Lot-specific COAs ship with every order.
We cook the raw botanical powder into the selected carrier. The botanical carries polar phenolics, flavonoid glycosides, and related extractable fractions. Those markers support antioxidant and skin-conditioning cosmetic stories. This is not a solvent isolate or a standardized marker extract. Lot identity appears on the COA and TDS.
This is a ready-to-use cosmetic extract stock, not a finished consumer product and not a standardized marker isolate. We cook the raw botanical powder into the selected hydroglycerin or oil carrier. Aqueous lots are released on pH, organoleptic, TAMC, and TYMC (total counts only). Oil macerates are released on organoleptic only. A sample COA is on this page; the lot-specific COA ships with the order.
Download sample Certificate of AnalysisStatements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.