Role of topical peptides in preventing or treating aged skin
Review of matrikine signal peptides that stimulate ECM components at the dermal-epidermal junction, the same cosmetic mechanism class as KGHK-derived peptides.
CT-3 cosmetic peptide suspension · choose base, strength, and preservation
Caprooyl Tetrapeptide-3 is a caproic-acid lipopeptide sold as a cosmetic raw material. Chemical catalogs list CAS 1012317-71-3 for caprooyl-Lys-Gly-His-Lys (about 565.7 g/mol, free base). A separate PubChem name record describes a different connectivity, so the lot certificate of analysis controls the structure supplied.
Caprooyl Tetrapeptide-3 · CAS 1012317-71-3
Caprooyl Tetrapeptide-3 is a caproic-acid (hexanoyl) lipopeptide used as a cosmetic raw material. Public records do not all describe the same connectivity. Chemical catalogs assign CAS 1012317-71-3 to caprooyl-Lys-Gly-His-Lys, formula C26H47N9O5, about 565.7 g/mol for the free base. PubChem CID 71599291, also titled Caprooyl tetrapeptide-3, is formula C24H42N8O7 and 554.6 g/mol, a different structure. This page does not show a structure drawing.
Supplier technical files for the trade name ChroNOline describe a lipopeptide of four amino acids linked to caproic acid, in a glycerin, water, and dextran blend. That is supplier literature, not an independent clinical study. Formulate Labs supplies the INCI as an aqueous suspension in 35% glycerin/water or Sea Kelp Bioferment, at 0.05% or a 0.5% lab concentrate. The lot certificate of analysis controls which structure was supplied.
Catalog identity often cited for the KGHK form: CAS 1012317-71-3. Separate name record: PubChem CID 71599291.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs supplies Caprooyl Tetrapeptide-3 (INCI) only and does not offer competitor trade-name SKUs.
Caprooyl Tetrapeptide-3 (Chronoline) shares the KGHK matrikine core documented in cosmetic literature for dermal-epidermal junction proteins, laminin, and fibronectin support. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Review of matrikine signal peptides that stimulate ECM components at the dermal-epidermal junction, the same cosmetic mechanism class as KGHK-derived peptides.
Clinical work on the acetylated KGHK tetrapeptide reporting ECM and follicle-anchoring endpoints; relevant mechanistic context for the caprooyl-KGHK Chronoline sequence.
Covers matrikine biology and GHK-family peptide effects on laminin, fibronectin, and skin matrix remodeling pathways relevant to DEJ-focused cosmetic actives.
Peer-reviewed summary of signal peptides used in anti-aging cosmetic formulas, including matrikine and ECM-support sequences.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the CT-3 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.