CT-3 cosmetic peptide suspension · choose base, strength, and preservation
Caprooyl Tetrapeptide-3 is a biomimetic signaling peptide, found in ChroNOline™-class actives (which Formulate Labs does not sell), engineered to visibly reduce fine lines and wrinkles by reinforcing the dermal-epidermal junction.
Cap-Pro-Gly-Gln · CAS 1012317-71-3
Caprooyl Tetrapeptide-3 is a biomimetic lipopeptide engineered to mimic the active signaling fragments of transforming growth factor-beta (TGF-β), focusing on targeted extracellular matrix (ECM) maintenance. By interacting with cellular communication pathways, Caprooyl Tetrapeptide-3 stimulates the synthesis of critical structural proteins at the dermal-epidermal junction (DEJ)—specifically collagen VII, laminin-5, and fibronectin. Reinforcing this crucial anchoring layer helps prevent the age-related flattening of the DEJ that contributes to skin sagging, leading to enhanced skin firmness, elasticity, and a clinically measurable reduction in fine line and wrinkle depth.
Market context: — Caprooyl Tetrapeptide-3 is positioned as a rapid-action biomimetic ingredient designed to visibly reduce the appearance of fine lines and wrinkles within a 28-day cellular turnover cycle by structurally reinforcing the dermal-epidermal junction. It is also marketed as an anti-fatigue and cellular energy booster that supports mitochondrial function to revitalize dull, mature skin profiles, and promoted as a highly stable, skin-penetrating, and preservative-free active for premium anti-aging and intensive firming protocols. Formulate Labs supplies Caprooyl Tetrapeptide-3 only and does not offer competitor trade-name SKUs, such as ChroNOline™.
Formulate Labs offers Caprooyl Tetrapeptide-3 in highly compatible aqueous suspensions, ideal for seamless integration into diverse cosmetic formulations. Our standard 0.1% suspension, crafted with glycerin and water, provides an effective and easy-to-use format for commercial products, while our 1% lab concentrate offers higher potency for focused research and development. This highly water-soluble peptide also exhibits perfect compatibility with Sea Kelp Bioferment as an alternative stock carrier.
We supply the peptide on its own as a finished aqueous suspension in two carriers - a 35% glycerin / water base for maximum formulation flexibility, or dosed directly into our single-origin Sea Kelp Bioferment. Both ship at the ChronolineTM-equivalent reference of 0.05% or our 10X lab concentrate at 0.5%.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs supplies Caprooyl Tetrapeptide-3 (INCI) only and does not offer competitor trade-name SKUs.
Caprooyl Tetrapeptide-3 (Chronoline) shares the KGHK matrikine core documented in cosmetic literature for dermal-epidermal junction proteins, laminin, and fibronectin support. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Review of matrikine signal peptides that stimulate ECM components at the dermal-epidermal junction, the same cosmetic mechanism class as KGHK-derived peptides.
Clinical work on the acetylated KGHK tetrapeptide reporting ECM and follicle-anchoring endpoints; relevant mechanistic context for the caprooyl-KGHK Chronoline sequence.
Covers matrikine biology and GHK-family peptide effects on laminin, fibronectin, and skin matrix remodeling pathways relevant to DEJ-focused cosmetic actives.
Peer-reviewed summary of signal peptides used in anti-aging cosmetic formulas, including matrikine and ECM-support sequences.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the CT-3 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
