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Peer-reviewed reference cited in Deep Research evidence brief.
Andrographis Paniculata Extract · 5% aqueous hydroglycerin stock
Experience the power of Andrographis Paniculata Extract from Formulate Labs, a fixed 5% hydroglycerin stock standardized for key diterpene lactone actives like andrographolide. Known by traditional names such as King of Bitters, our INCI material offers advanced cosmetic benefits for modern skincare.
A plant known for potent botanical actives.
Botanical Identity: Andrographis Paniculata Extract is derived from the *Andrographis paniculata* plant. Trade Names: Known as Kalmegh and King of Bitters, Formulate Labs provides the INCI-specified material, not proprietary supplier SKUs.
Dual mechanism: Andrographolide modulates the brain-skin axis and helps mitigate the visible effects of oxidative stress by activating the Nrf2 signaling pathway, supporting natural antioxidant enzymes (SOD and catalase). Furthermore, it helps soothe the skin by downregulating pro-inflammatory cytokines (TNF-α and IL-6) and targeting cutaneous TRPV3 channels to alleviate feelings of discomfort and pruritus.
Use levels: Formulate Labs supplies this extract as a 5% hydroglycerin stock, recommended for use at 0.5% – 2.0% in formulations.
Market context: Competitors position *Andrographis Paniculata* Extract around several key narratives: 'Neuro-Cosmetic Activation' (connecting internal soothing to external benefits like reduced fatigue and radiance), 'Receptor-Targeted Relief' (linking bitterness to epidermal bitter taste receptor activation for soothing reactive skin), and 'Stem Cell Preservation' (emphasizing protection of epidermal stem cells from UV-induced damage and anti-photoaging).
Pricing context: Publicly available data for cosmetic-grade liquid *Andrographis paniculata* extracts is sparse. Value-added, solubilized liquid extracts typically command a premium over raw powder ($10-$50/kg). Formulate Labs' hydroglycerin-based extract is priced at $98.00 for a 500 g sample, $150.00 for 1 kg, and $2,040.00 ($120.00/kg) for a 17 kg pail.
We ship a fixed 5% extract blend with selectable preservation - ready to meter into water-phase formulas at the use rates in the formulation guide below.*
Trade names (Kalmegh, King of Bitters) refer to the botanical source, while Formulate Labs supplies the INCI-specified material.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
* Structure/function statements based on published cosmetic in-vitro studies. Not evaluated for, and not intended to, diagnose, treat, cure, or prevent any disease.
Andrographis Paniculata Extract is documented in cosmetic peptide/protein literature. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the hydroglycerin stocks on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
Bulk composition at fixed 5% Andrographis Paniculata Extract loading. Base carrier components scale proportionally when preservative is added; extract stays at 5%. Updates dynamically when you change base or preservation above. Full CAS disclosure is on the SDS/TDS for the selected variant (FL-APE-W1-MBS4-5PCT-001).
SDS + TDS are issued per base and preservative combination. Links swap when you change selections above. COA is batch-specific and ships with the order.
Statements contained on this page (including any marked with *) have not been evaluated by the U.S. Food and Drug Administration. This product is a cosmetic raw material and is not intended to diagnose, treat, cure, or prevent any disease.