AT-3 cosmetic peptide suspension · choose base, strength, and preservation
Acetyl Tetrapeptide-3 is a biomimetic signal peptide that strengthens hair follicle anchoring and dermal-epidermal junctions, a key peptide found in Capixyl™-class actives, which Formulate Labs does not sell.
Ac-Lys-Asp-Val-Tyr · CAS 827306-88-7
Acetyl Tetrapeptide-3 (Ac-KGHK) is a biomimetic signal peptide engineered to mimic a natural extracellular matrix (ECM) protein fragment, designed for cosmetic applications aimed at structural reinforcement. It strategically stimulates the synthesis of crucial ECM proteins, notably laminin and collagens III and VII, to strengthen hair follicle anchoring and fortify the dermal-epidermal junction, thereby supporting enhanced hair resilience and skin integrity.
Market context: While Acetyl Tetrapeptide-3 is prominently featured in trademarked complexes like Capixyl™ (a trade name blending the peptide with *Trifolium pratense* extract, which Formulate Labs does not sell), Formulate Labs exclusively supplies the standalone INCI. This approach offers formulators maximum flexibility and cost-efficiency, freeing them from proprietary blend restrictions and enabling tailored product development.
Formulate Labs typically provides Acetyl Tetrapeptide-3 in a convenient 0.1% standard glycerin suspension, ideal for seamless incorporation into a wide range of cosmetic formulations. This pre-solubilized liquid blend offers formulation flexibility and simplifies handling, allowing chemists to achieve precise active concentrations with ease.
We supply the peptide on its own (without the clover extract) as a finished aqueous suspension in two carriers - a 35% glycerin / water base for maximum formulation flexibility, or dosed directly into our single-origin Sea Kelp Bioferment for formulators who want to ship a pre-built hydrating active in one drop. Both ship at the CapixylTM-equivalent peptide reference of 0.035%, or our 10X lab concentrate at 0.35%.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Acetyl Tetrapeptide-3 refers to the pure INCI ingredient, distinct from trademarked blends like Capixyl™, which Formulate Labs does not supply.
Acetyl Tetrapeptide-3 (the Capixyl peptide sequence) is documented in peer-reviewed hair-science literature for follicle anchoring, extracellular-matrix support, and anagen/telogen balance. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Randomized study of acetyl tetrapeptide-3 with red-clover isoflavones in hair-care formulas, reporting improved anagen/telogen ratios versus placebo over 4 months.
Peer-reviewed review of cosmetic peptide classes with a dedicated section on acetyl hexapeptide/tetrapeptide hair-active sequences and their proposed mechanisms.
Seminal review of matrikine and signal peptides in leave-on skincare, useful context for how short biomimetic sequences are studied in cosmetic formulations.
Overview of peptide cosmeceuticals including hair- and skin-active biomimetic sequences and the difference between cosmetic and drug claim language.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the AT-3 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
