AT-11 cosmetic peptide suspension · choose base, strength, and preservation
Acetyl Tetrapeptide-11 is a biomimetic signal peptide that reinforces skin structure, enhancing density, elasticity, and smoothness for advanced firming and anti-aging formulations; its mechanism of action is found in Syniorage™-class actives, though Formulate Labs does not sell these trade-name products.
Ac-Prolisel tetrapeptide (syndecan-1 mimic) · CAS 928006-89-7
Acetyl Tetrapeptide-11 is a synthetic biomimetic signal peptide specifically engineered to combat the structural degradation often seen in mature skin by targeting the dermal-epidermal junction (DEJ). This peptide functions by stimulating the synthesis of syndecan-1–a crucial small proteoglycan–and type XVII collagen, an essential structural protein within hemidesmosomes. This dual-action mechanism works to reinforce epidermal cohesion and intercellular adhesion, effectively improving skin density, elasticity, and surface smoothness for premium firming and anti-aging formulations.
Market context: — The cosmetic peptide market features ingredients like Acetyl Tetrapeptide-11, which is found in Syniorage™-class actives from suppliers like BASF, where it is positioned for epidermal cohesion enhancement in mature skin. This peptide is also often blended with other ingredients, such as Acetyl Tetrapeptide-9 in Replexium®-class actives, to achieve comprehensive anti-aging effects by targeting both epidermal and dermal matrices. Formulate Labs exclusively supplies the pure INCI ingredient, Acetyl Tetrapeptide-11, for custom formulation, and we do not sell or distribute any competitor trade-name SKUs.
Formulate Labs offers Acetyl Tetrapeptide-11 in high-purity, standardized suspensions, typically at 1500 ppm or 0.1% in glycerin, ensuring optimal stability and ease of integration into diverse cosmetic bases. Our rigorously tested carriers are designed to maintain the peptide’s structural integrity and bioavailability, providing a reliable foundation for your advanced formulations.
We supply it as a finished aqueous suspension in two carriers - a 35% glycerin / water base for maximum formulation flexibility, or dosed directly into our single-origin Sea Kelp Bioferment. Both ship at the ProliselTM-equivalent reference of 0.01% or our 10X lab concentrate at 0.1%.
These attributes are assessments based on the ingredient deck and the supplier information available to us. They are not third-party certifications (no Kosher, Halal, Vegan, or similar certifying body has audited or issued a certificate for this material). If your finished product requires a specific certified status, please reach out and we’ll walk through what we can document.
Every lot is produced to order in our AI-powered robotic factory. Nothing sits on a warehouse shelf going stale - you get a date-of-manufacture-fresh batch every time.
Formulate Labs provides Acetyl Tetrapeptide-11 as a pure INCI ingredient for custom formulation, and we do not supply trade-name SKUs such as Syniorage™ or Replexium®.
Acetyl Tetrapeptide-11 (Prolisel) is a syndecan-1-mimetic tetrapeptide discussed in cosmetic hydration and matrix-support literature for resilient, moisturized-looking skin. These are independent, third-party papers we link for formulators evaluating mechanism, tolerability, and published panel data. We did not conduct this research and do not guarantee replication in your finished formula.
Review of epidermal water-transport biology underpinning the hydration-positioned cosmetic rationale for syndecan- and aquaporin-mimetic peptides like Prolisel.
Seminal review of signal peptides that support skin hydration and matrix integrity in leave-on moisturizers and serums.
Peer-reviewed overview of hydration- and barrier-positioned cosmetic peptides and the structure/function claim framing for finished products.
Clinician-oriented review of topical peptide cosmeceuticals covering hydration mechanisms and evidence review practices for formulators.
These citations are provided for informational and formulation-research purposes only. Study designs, concentrations, vehicle systems, and populations vary and may not match the suspensions on this page. Published results do not constitute FDA or EU cosmetic claim substantiation for your brand. Always review the primary literature and consult your regulatory counsel before making structure/function statements on finished products.
This is the per-ingredient composition of the suspension as it ships. Updates dynamically when you change the base, strength, or preservation system above. The peptide line shows the AT-11 loading; the preservative line shows the supplier-blend percentage with its sub-ingredients nested below.
SDS + TDS are issued per recipe (each base / preservative combination has its own regulatory paperwork). The links below swap when you change your selection above. COA is batch-specific and ships with the order.
